摘要目的 分析婴幼儿先天性白内障术后无晶状体性青光眼的发生率、发生时间及类型.方法 回顾2010年1月至2014年1月于郑州大学第一附属医院眼科行先天性白内障手术的≤2周岁的患儿资料.分析患儿先天性白内障的手术年龄、手术方式,观察白内障手术后青光眼的发生率、发生时间及类型.结果 205例324眼被纳入观察对象,平均手术年龄13.9(2 ～24)个月,手术方式均为白内障摘除联合后囊环形撕囊联合前段玻璃体切割,术后随访47.6(22 ～63)个月.29例37眼被诊断为先天性白内障术后无晶状体性青光眼,发生率为11.42％.发生无晶状体性青光眼的患儿白内障手术平均年龄6.8(2～12)个月.未发生青光眼的176例287眼白内障平均手术年龄14.1(10 ～24)个月.37眼青光眼中,早发性闭角型青光眼9眼,发生率为2.78％;发生时间为白内障术后2 ～ 12(4.2±2.6)个月;迟发性青光眼28眼,发生率为8.64％;其中2眼为闭角型,26眼为开角型;发生时间为白内障术后18 ～64(37.5±11.0)个月.结论 婴幼儿先天性白内障术后无晶状体性青光眼的发生率为11.42％;发生时间为白内障术后2～64个月;迟发性开角型青光眼较早发性闭角型青光眼多见.

abstractsObjective To investigate the incidence,occurrence time and types of aphakic glaucoma following infantile congenital cataract surgery.Methods The records of children who underwent surgery for congenital cataract within the first 24 months of life between January 2010 and January 2014 at the First Affiliated Hospital of Zhengzhou University were retrospectively reviewed.Children with preoperative conditions associated with glaucoma were excluded.The following parameters were ascertained:age received cataract surgery,operation method,the incidence,occurrence time and types of glaucoma.Results A total of 205 patients (324 eyes) with an average surgery age of 13.9 months were included,and the mean follow-up time was 47.6 months.The operation method was cataract extraction combined with posterior continuous circular capsulorhexis and anterior vitrectomy.Twenty-nine patients (37 eyes,11.42％) had subsequent development of aphakic glaucoma,9 eyes of which (2.78％) developed early onset angle closed glaucoma,and the occurrence time was (4.2 ±2.6) months after cataract surgery;28 eyes (8.64％) developed late onset open angle glaucoma,26 of which was angle open glaucoma,and the rest two was angle closed glaucoma.The occurrence time was (37.5 ± 11.0) months after cataract surgery.Twenty-nine patients (37 eyes) developed aphakic glaucoma had cataract surgery within 2 to 12 months (6.8 months on average).The rest 176 patients (287 eyes) who did not develop glaucoma had cataract surgery at 10 to 24 months (14.1 months on average).Conclusions The incidence of aphakic glaucoma following infantile congenital cataract surgery is 11.42％.Aphakic glaucoma is divided into two types of early onset angle closed glaucoma and late onset open angle glaucoma.The occurence time of glaucoma was 2 months to 64 months after cataract surgery.Late onset open angle glaucoma is the most common type.