摘要目的:探讨两种综合习服训练方案对大学生运动病（MSD）和视觉诱发运动病（VIMSD）症状和生理指标的改善效果。方法:随机对照试验。纳入2023年12月至2024年6月在华北理工大学招募的92例患MSD/VIMSD的大学生，按随机数字表法分为电动转椅组和视动笼转椅组。两组均接受28 d综合习服训练（电动/视动笼转椅7 d+四柱秋千14 d+“天转地转”平衡操7 d）。训练前、训练后第1天、第8周及第12周进行转椅诱发并记录Graybiel评分、交感神经指标［皮肤电反应（SCR）等］、自主神经功能指标［相邻RR间期差值的均方根（rMSSD）等］和心率等共9项主、客观指标。采用广义估计方程分析不同随访时点的组间差异。结果:共纳入92例患MSD/VIMSD的大学生，男40例，女52例，年龄22（20，23）岁；其中电动转椅组和视动笼转椅组各46例。训练后第1天，两组Graybiel评分均降低（均 P<0.001），电动转椅组降幅更大［14（8，18）分比8（0，16）分， P=0.028］。生理指标比较结果显示，电动转椅组交感神经指标在各随访时间点改善更明显（均 P<0.05），而视动笼转椅组自主神经功能指标在各随访时间点调节更佳（均 P<0.05）。随访12周，电动转椅组交感神经指标自训练后第1天至第12周持续改善（β值：0.11~2.35，均 P<0.01），视动笼转椅组自主神经功能指标较治疗前改善并在12周内稳定（β值：-52.84~-0.17，均 P<0.01）。 结论:两种方案均能有效缓解MSD/VIMSD症状，疗效持续12周。电动转椅组降低交感神经激活的效果更优，视动笼转椅组调节自主神经平衡的能力更佳，可为个性化干预提供依据。

abstractsObjective:To examine the effects of two complete habituation training programs onsubjective and objective indicators in college students with motion sickness (MSD) and visually induced motion sickness (VIMSD).Methods:A randomized controlled trial was conducted. A total of 92 college students diagnosed with MSD/VIMSD, recruited from December 2023 to June 2024, were randomized into an electric rotating chair group and an optokinetic drum rotating chair group. Both groups underwent a 28-day comprehensive habituation training program (7 days of electric/optokinetic drum rotating chair training, 14 days of four-pole swing training, and 7 days of "sky-earth rotation" balance exercises). Graybiel scores, sympathetic nervous system indicators [skin conductance response (SCR), etc.], autonomic nervous function indicators [root mean square of successive RR interval differences (rMSSD), etc], heart rate (HR), and other objective/subjective parameters (9 indicators) were recorded and analyzed before training, and one day, eight weeks and 12 weeks post-training. General demographic data were recorded for both groups. Within-and between-group differences were analyzed using parametric (paired/independent t-tests) or nonparametric tests (Wilcoxon/K-S tests), respectively. Intergroup differences across different follow-up time points were assessed by generalized estimating equations. Results:A total of 92 college students with MSD/VIMSD were enrolled, including 40 males and 52 females with a median age of 22 years ( IQR: 20-23). Forty-six participants were assigned to the electric rotating chair group and 46 to the optokinetic drum rotating chair group. On day one post-training, Graybiel scores significantly decreased in both groups (all P<0.001), with a greater reduction observed in the electric rotating chair group [14 (8, 18) points vs 8 (0, 16) points, P=0.028]. Physiological results showed that the electric rotating chair group demonstrated superior improvements in sympathetic nervous system indicators (all P<0.05). The optokinetic drum rotating chair group exhibited better regulation of autonomic nervous function indicators (all P<0.05). With a follow-up of 12-weeks, the electric rotating chair group maintained sustained improvements in sympathetic indicators (β-range: 0.11 to 2.35, all P<0.01). The optokinetic drum group showed long-term stabilization of autonomic function parameters (β-range:-52.84 to -0.17, all P<0.01). Conclusions:Both comprehensive interventions significantly alleviate MSD/VIMSD symptoms, with effects sustained for 12 weeks. The electric rotating chair group is more effective in reducing sympathetic nerve activation, while the optokinetic drum rotating chair group demonstrates superior regulation of autonomic nervous balance, providing evidence for personalized therapeutic strategies.