摘要目的:探讨全息影像技术在颅内肿瘤手术患者中应用的可行性及临床价值。方法:选取首都医科大学附属北京天坛医院2020年11月至2021年3月收治的颅内肿瘤患者40例，采用随机数字表法将患者分为试验组（20例）、对照组（20例）。试验组患者行全息影像技术辅助开颅手术，对照组患者行常规开颅手术。记录患者术前及术后7 d的Karnofsky功能状态评分，应用焦虑自评量表评估患者家属的焦虑情绪。结果:全部患者术后12 h复查头颅CT均无瘤腔高密度影，术后72 h复查头颅磁共振成像（MRI），试验组17例肿瘤全切除，3例为大部分切除；对照组16例肿瘤全切除，4例大部分切除。试验组1例术后左下肢肌力Ⅱ级，出院时恢复至Ⅴ-级。对照组2例术后左侧肢体肌力Ⅲ级，出院时恢复至Ⅴ级。术前试验组与对照组Karnofsky评分为60、70、80、90、100分的患者分别为1、5、8、6、0例和0、4、9、6、1例，差异无统计学意义（ P>0.05）；术后试验组与对照组Karnofsky评分为50、60、70、80、90、100分的患者分别为1、0、0、7、9、3例和0、3、6、4、5、2例，差异有统计学意义（ P＝0.018）。试验组手术前后Karnofsky评分差异有统计学意义（ P＝0.029），对照组手术前后差异无统计学意义（ P＝0.241）。试验组患者家属无焦虑、轻度焦虑、中度焦虑、重度焦虑患者术前分别为8、9、2、1例，术后分别为9、9、2、0例；对照组患者家属无焦虑、轻度焦虑、中度焦虑、重度焦虑患者术前分别为3、4、8、4例，术后分别为2、5、9、4例。试验组术前焦虑水平较对照组低，差异有统计学意义（ P＝0.016）；试验组患者术后焦虑水平较对照组低，差异有统计学意义（ P＝0.002）。 结论:全息影像技术在颅内肿瘤术前可以辅助制订精准的手术方案；术中可直观地显示肿瘤与周围重要组织的解剖关系，减少手术副损伤并可减少患者家属的焦虑情绪。

abstractsObjective:To explore the feasibility and clinical value of holographic image technology in intracranial tumor surgery.Methods:A total of 40 patients with intracranial tumors in Beijing Tiantan Hospital, Capital Medical University from November 2020 to March 2021 were randomly divided into the experimental group (20 cases) and the control group (20 cases) based on the random number table. Patients in the experimental group underwent craniotomy assisted by holographic technology, while patients in the control group underwent conventional craniotomy. The Karnofsky performance status scores of patients before the operation and 7 days after the operation were recorded, and the self-rating anxiety scale was applied to evaluate the anxiety of the patients' families.Results:The head CT 12 h after surgery showed no tumor cavity hyperdensity in all patients. The head magnetic resonance imaging (MRI) 72 h after surgery revealed 17 cases of total resection and 3 cases of subtotal resection in the experimental group; in the control group, there were 16 cases of total resection and 4 cases of subtotal resection. In the experimental group, 1 patient's left lower limb muscle strength was grade Ⅱ after the operation and recovered to grade Ⅴ-at discharge. In the control group, the left limb muscle strength of 2 patients was grade Ⅲ after the operation and recovered to grade Ⅴ at discharge. The patients with Karnofsky scores of 60, 70, 80, 90, 100 scores were found in 1 case, 5 cases, 8 cases, 6 cases, 0, respectively of the experimental group and 0, 4 cases, 9 cases, 6 cases, 1 case, respectively of the control group before the operation, and the difference was statistically significant ( P > 0.05); the patients with Karnofsky scores of 50, 60, 70, 80, 90, 100 scores were found in 1 case, 0, 0, 7 cases, 9 cases,3 cases, respectively of the experimental group and 0, 3 cases, 6 cases, 4 cases, 5 cases, 2 cases, respectively of the control group after the operation, and the difference was statistically significant ( P = 0.018). The difference of Karnofsky score before and after the operation in the experimental group was statistically significant ( P = 0.029), while there was no statistically significant difference in the Karnofsky score before and after the operation in the control group ( P = 0.241). There were 8 cases, 9 cases, 2 cases and 1 case of non-anxiety, mild anxiety, moderate anxiety, severe anxiety, respectively in the experimental group and 3 cases, 4 cases, 8 cases and 4 cases of non-anxiety, mild anxiety, moderate anxiety, severe anxiety, respectively in the control group before the operation; there were 9 cases, 9 cases, 2 cases and 0 case of non-anxiety, mild anxiety, moderate anxiety, severe anxiety, respectively in the experimental group and 2 cases, 5 cases, 9 cases and 4 cases of non-anxiety, mild anxiety, moderate anxiety, severe anxiety, respectively in the control group after the operation. The preoperative and postoperative anxiety scores of the experimental group were all lower than those of the control group, and the differences were statistically significant (preoperative P = 0.016,postoperative P = 0.002). Conclusions:Holographic technology can assist in formulating an accurate surgical plan before intracranial tumor surgery, intuitively display the anatomical relationship between the tumor and its surrounding important tissues during operation, reduce the surgical side injuries and decrease the anxiety of the patients' family.