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The biomechanical stability of a novel totally bioabsorbable self-retaining PLA/nano-sized β-TCP cervical spine interbody fusion device in single level ACDF models

摘要PURPOSE The purpose of this study was to compare the biomechanical stability provided by a novel PLA/ nano-sized β-TCP bioabsorbable self-retaining cervical fusion cage (BCFC) device, and compare it with tricortical iliac crest bone graft and two types of PEEK cages according to their shape and anchoring design, and furtherly to compare with tricortical iliac crest bone graft plus anterior cervical plate (ACP).METHODS Quasistatic nonconstraining torques (maximum 1.5NM) induced flexion, extension, lateral bending (± 1.5 NM) , and axial rotation (± 1.5 NM) on 32 sheep cervical spines (C2-C5).The motion segment C3-C4 was firstly tested intact, the following groups were tested after complete discectomy: autologous tricortical iliac crest bone graft, Wego cage, Solis cage, and BCFC.Further, the group of autologous bone graft was evaluated with ACP.The mean range of motion (ROM) was calculated from the load-displacement curves.RESULTS No significant difference in ROM between two types of PEEK cages and BCFC could be observed in flexion and extension, BCFC device significantly decreased ROM in lateral bending and axial rotation compared with all implants.No significant difference in ROM between BCFC and bone graft plus ACP could be determined in lateral bending and axial rotation.CONCLUSIONS BCFC device showed comparable stability to autologous tricortical iliac crest bone graft and PEEK cages in single level ACDF models, it may be a viable altemative to current PEEK cages and anterior plate devices.

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