换一批
换一批摘要Background: Acquired immune deficiency syndrome (AIDS) has caused catastrophic consequences to human society.During the infection process, the HIV-1 gpl20 glycoprotein undergoes a series of conformational changes while sequentially interacting with its receptor and co-receptor located on the host cell surface.Although the gpl20 crystal structural cores bound and pre-bound by the CD4 are currently available, the details of dynamics involved in conformational equilibrium and transition in relation to its function have remained elusive.
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作者
学术成果认领
关键词
gp120dynamics and functionconformational equilibrium and transitionessential dynamicsfree energy landscape
会议名称：
第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会
南京
2014年
发布时间
2016-04-18
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