换一批A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer
作者：
Wu, Lang [1]
;
Shi, Wei [2]
;
Long, Jirong [3]
;
Guo, Xingyi [4]
;
Michailidou, Kyriaki [5]
;
Beesley, Jonathan [6]
;
Bolla, Manjeet K. [7]
;
Shu, Xiao-Ou [8]
;
Lu, Yingchang [9]
;
Cai, Qiuyin [10]
;
Al-Ejeh, Fares [11]
;
Rozali, Esdy [12]
;
Wang, Qin [13]
;
Dennis, Joe [14]
;
Li, Bingshan [15]
;
Zeng, Chenjie [16]
;
Feng, Helian [17]
;
Gusev, Alexander [18]
;
Barfield, Richard T. [19]
;
Andrulis, Irene L. [20]
;
Anton-Culver, Hoda [21]
;
Arndt, Volker [22]
;
Aronson, Kristan J. [23]
;
Auer, Paul L. [24]
;
Barrdahl, Myrto [25]
;
Baynes, Caroline [26]
;
Beckmann, Matthias W. [27]
;
Benitez, Javier [28]
;
Bermisheva, Marina [29]
;
Blomqvist, Carl [30]
;
Bogdanova, Natalia V. [31]
;
Bojesen, Stig E. [32]
;
Brauch, Hiltrud [33]
;
Brenner, Hermann [34]
;
Brinton, Louise [35]
;
Broberg, Per [36]
;
Brucker, Sara Y. [37]
;
Burwinkel, Barbara [38]
;
Caldes, Trinidad [39]
;
Canzian, Federico [40]
;
Carter, Brian D. [41]
;
Castelao, J. Esteban [42]
;
Chang-Claude, Jenny [43]
;
Chen, Xiaoqing [44]
;
Cheng, Ting-Yuan David [45]
;
Christiansen, Hans [46]
;
Clarke, Christine L. [47]
;
Collee, Margriet [48]
;
Cornelissen, Sten [49]
;
Couch, Fergus J. [50]
;
Cox, David [51]
;
Cox, Angela [52]
;
Cross, Simon S. [53]
;
Cunningham, Julie M. [54]
;
Czene, Kamila [55]
;
Daly, Mary B. [56]
;
Devilee, Peter [57]
;
Doheny, Kimberly F. [58]
;
Dork, Thilo [59]
;
dos-Santos-Silva, Isabel [60]
;
Dumont, Martine [61]
;
Dwek, Miriam [62]
;
Eccles, Diana M. [63]
;
Eilber, Ursula [64]
;
Eliassen, A. Heather [65]
;
Engel, Christoph [66]
;
Eriksson, Mikael [67]
;
Fachal, Laura [68]
;
Fasching, Peter A. [69]
;
Figueroa, Jonine [70]
;
Flesch-Janys, Dieter [71]
;
Fletcher, Olivia [72]
;
Flyger, Henrik [73]
;
Fritschi, Lin [74]
;
Gabrielson, Marike [75]
;
Gago-Dominguez, Manuela [76]
;
Gapstur, Susan M. [77]
;
Garcia-Closas, Montserrat [78]
;
Gaudet, Mia M. [79]
;
Ghoussaini, Maya [80]
;
Giles, Graham G. [81]
;
Goldberg, Mark S. [82]
;
Goldgar, David E. [83]
;
Gonzalez-Neira, Anna [84]
;
Guenel, Pascal [85]
;
Hahnen, Eric [86]
;
Haiman, Christopher A. [87]
;
Hakansson, Niclas [88]
;
Hall, Per [89]
;
Hallberg, Emily [90]
;
Hamann, Ute [91]
;
Harrington, Patricia [92]
;
Hein, Alexander [93]
;
Hicks, Belynda [94]
;
Hillemanns, Peter [95]
;
Hollestelle, Antoinette [96]
;
Hoover, Robert N. [97]
;
Hopper, John L. [98]
;
Huang, Guanmengqian [99]
;
Humphreys, Keith [100]
;
Hunter, David J. [101]
;
Jakubowska, Anna [102]
;
Janni, Wolfgang [103]
;
John, Esther M. [104]
;
Johnson, Nichola [105]
;
Jones, Kristine [106]
;
Jones, Michael E. [107]
;
Jung, Audrey [108]
;
Kaaks, Rudolf [109]
;
Kerin, Michael J. ;
Khusnutdinova, Elza ;
Kosma, Veli-Matti ;
Kristensen, Vessela N. ;
Lambrechts, Diether ;
Le Marchand, Loic ;
Li, Jingmei ;
Lindstrom, Sara ;
Lissowska, Jolanta ;
Lo, Wing-Yee ;
Loibl, Sibylle ;
Lubinski, Jan ;
Luccarini, Craig ;
Lux, Michael P. ;
MacInnis, Robert J. ;
Maishman, Tom ;
Kostovska, Ivana Maleva ;
Mannermaa, Arto ;
Manson, Joann E. ;
Margolin, Sara ;
Mavroudis, Dimitrios ;
Meijers-Heijboer, Hanne ;
Meindl, Alfons ;
Menon, Usha ;
Meyer, Jeffery ;
Mulligan, Anna Marie ;
Neuhausen, Susan L. ;
Nevanlinna, Heli ;
Neven, Patrick ;
Nielsen, Sune F. ;
Nordestgaard, Borge G. ;
Olopade, Olufunmilayo I. ;
Olson, Janet E. ;
Olsson, Hakan ;
Peterlongo, Paolo ;
Peto, Julian ;
Plaseska-Karanfilska, Dijana ;
Prentice, Ross ;
Presneau, Nadege ;
Pylkas, Katri ;
Rack, Brigitte ;
Radice, Paolo ;
Rahman, Nazneen ;
Rennert, Gad ;
Rennert, Hedy S. ;
Rhenius, Valerie ;
Romero, Atocha ;
Romm, Jane ;
Rudolph, Anja ;
Saloustros, Emmanouil ;
Sandler, Dale P. ;
Sawyer, Elinor J. ;
Schmidt, Marjanka K. ;
Schmutzler, Rita K. ;
Schneeweiss, Andreas ;
Scott, Rodney J. ;
Scott, Christopher G. ;
Seal, Sheila ;
Shah, Mitul ;
Shrubsole, Martha J. ;
Smeets, Ann ;
Southey, Melissa C. ;
Spinelli, John J. ;
Stone, Jennifer ;
Surowy, Harald ;
Swerdlow, Anthony J. ;
Tamimi, Rulla M. ;
Tapper, William ;
Taylor, Jack A. ;
Terry, Mary Beth ;
Tessier, Daniel C. ;
Thomas, Abigail ;
Thone, Kathrin ;
Tollenaar, Rob A. E. M. ;
Torres, Diana ;
Truong, Therese ;
Untch, Michael ;
Vachon, Celine ;
Van den Berg, David ;
Vincent, Daniel ;
Waisfisz, Quinten ;
Weinberg, Clarice R. ;
Wendt, Camilla ;
Whittemore, Alice S. ;
Wildiers, Hans ;
Willett, Walter C. ;
Winqvist, Robert ;
Wolk, Alicja ;
Xia, Lucy ;
Yang, Xiaohong R. ;
Ziogas, Argyrios ;
Ziv, Elad ;
Dunning, Alison M. ;
Pharoah, Paul D. P. ;
Simard, Jacques ;
Milne, Roger L. ;
Edwards, Stacey L. ;
Kraft, Peter ;
Easton, Douglas F. ;
Chenevix-Trench, Georgia ;
Zheng, Wei
作者单位：
German Breast Grp GmbH, Neu Isenburg, Germany
[1]
Macedonian Acad Sci & Arts, Res Ctr Genet Engn & Biotechnol Georgi D Efrernov, Skopje, Macedonia
[2]
Northern Finland Lab Ctr Oulu, Lab Canc Genet & Tumor Biol, Oulu, Finland
[3]
Univ Hosp Heraklion, Hereditary Canc Clin, Iraklion, Greece
[4]
Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA USA
[5]
Univ Helsinki, Helsinki Univ Hosp, Dept Obstet & Gynecol, Helsinki, Finland
[6]
German Canc Res Ctr, Mol Genet Breast Canc, Heidelberg, Germany
[7]
Univ Hosp Cologne, Ctr Hereditary Breast & Ovarian Canc, Cologne, Germany
[8]
Univ Hosp Ulm, Dept Gynecol & Obstet, Ulm, Germany
[9]
Univ Leipzig, Inst Med Informat Stat & Epidemiol, Leipzig, Germany
[10]
NCI, Div Canc Epidemiol & Genet, Rockville, MD USA
[11]
Vanderbilt Univ, Dept Mol Physiol & Biophys, Vanderbilt Genet Inst, Nashville, TN 37232 USA
[12]
Curtin Univ, Curtin UWA Ctr Genet Origins Hlth & Dis, Perth, WA, Australia
[13]
McGill Univ, Montreal, PQ, Canada
[14]
Hannover Med Sch, Gynaecol Res Unit, Hannover, Germany
[15]
Columbia Univ, Mailman Sch Publ Hlth, Dept Epidemiol, New York, NY USA
[16]
Complejo Hosp Univ Santiago, SERGAS, Inst Invest Sanitaria Santiago Compostela IDIS, Genom Med Grp
[17]
Inst Canc Res, Breast Canc Now Toby Robins Res Ctr, London, England
[18]
Dana Farber Canc Inst, Dept Med Oncol, Boston, MA 02115 USA
[19]
Amer Canc Soc, Epidemiol Res Program, Atlanta, GA 30329 USA
[20]
CIBERONC Hosp Clin San Carlos, Med Oncol Dept, Madrid, Spain
[21]
Copenhagen Univ Hosp, Herlev & Gentofte Hosp, Dept Breast Surg, Herlev, Denmark
[22]
Stanford Univ, Sch Med, Dept Hlth Res & Policy Epidemiol, Stanford, CA 94305 USA
[23]
Univ Melbourne, Dept Pathol, Melbourne, Vic, Australia
[24]
Univ Sheffield, Acad Unit Pathol, Dept Neurosci, Sheffield, S Yorkshire, England
[25]
Univ Southampton, Canc Sci Acad Unit, Fac Med, Southampton, Hants, England
[26]
German Canc Res Ctr, Div Canc Epidemiol, Heidelberg, Germany
[27]
Vanderbilt Univ, Sch Med, Dept Med, Div Epidemiol,Vanderbilt Epidemiol Ctr,Vanderbilt, Nashville
[28]
Univ Chicago, Ctr Clin Canc Genet & Global Hlth, Chicago, IL 60637 USA
[29]
Univ Eastern Finland, Translat Canc Res Area, Kuopio, Finland
[30]
M Sklodowska Curie Inst, Ctr Oncol, Dept Canc Epidemiol & Prevent, Warsaw, Poland
[31]
Katholieke Univ Leuven, VIB, Ctr Canc Biol, Leuven, Belgium
[32]
NIEHS, Epidemiol Branch, NIH, Res Triangle Pk, NC 27709 USA
[33]
Univ Hawaii, Ctr Canc, Program Epidemiol, Honolulu, HI 96822 USA
[34]
Univ Med Ctr Hamburg Eppendorf, Inst Med Biometr & Epidemiol, Hamburg, Germany
[35]
London Sch Hyg & Trop Med, Dept Noncommunicable Dis Epidemiol, London, England
[36]
Queens Univ, Dept Publ Hlth Sci, Kingston, ON, Canada
[37]
Beckman Res Inst City Hope, Dept Populat Sci, Duarte, CA USA
[38]
Lund Univ, Dept Canc Epidemiol, Clin Sci, Lund, Sweden
[39]
Leiden Univ, Med Ctr, Dept Surg, Leiden, Netherlands
[40]
Univ Toronto, Dept Lab Med & Pathobiol, Toronto, ON, Canada
[41]
Fred Hutchinson Canc Res Ctr, Canc Prevent Program, 1124 Columbia St, Seattle, WA 98104 USA
[42]
Fox Chase Canc Ctr, Dept Clin Genet, 7701 Burholme Ave, Philadelphia, PA 19111 USA
[43]
Univ Tubingen, Dept Gynecol & Obstet, Tubingen, Germany
[44]
NIEHS, Biostat & Computat Biol Branch, NIH, Res Triangle Pk, NC USA
[45]
Hannover Med Sch, Dept Radiat Oncol, Hannover, Germany
[46]
Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden
[47]
Mayo Clin, Dept Lab Med & Pathol, Rochester, MN USA
[48]
Ist Nazl Tumori INT, Fdn IRCCS, Dept Res, Unit Mol Bases Genet Risk & Genet Testing, Milan, Italy
[49]
Helios Clin Berlin Buch, Dept Gynecol & Obstet, Berlin, Germany
[50]
Canc Council Victoria, Canc Epidemiol & Intelligence Div, Melbourne, Vic, Australia
[51]
Copenhagen Univ Hosp, Herlev & Gentofte Hosp, Copenhagen Gen Populat Study, Herlev, Denmark
[52]
Univ Hosp Leuven, Leuven Canc Inst, Dept Oncol, Leuven Multidisciplinary Breast Ctr, Leuven, Belgium
[53]
German Canc Res Ctr, Genom Epidemiol Grp, Heidelberg, Germany
[54]
Univ Hosp Herakl, Dept Med Oncol, Iraklion, Greece
[55]
Inst Canc Res, Div Genet & Epidemiol, London, England
[56]
Univ Cambridge, Dept Oncol, Ctr Canc Genet Epidemiol, Cambridge, England
[57]
Karolinska Inst, Inst Environm Med, Stockholm, Sweden
[58]
Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England
[59]
Mt Sinai Hosp, Lunenfeld Tanenbaum Res Inst, Fred A Litwin Ctr Canc Genet, Toronto, ON, Canada
[60]
Genome Inst Singapore, Human Genet, Singapore, Singapore
[61]
Erasmus MC Canc Inst, Family Canc Clin, Dept Med Oncol, Rotterdam, Netherlands
[62]
Curtin Univ, Sch Publ Hlth, Perth, WA, Australia
[63]
Dr Margarete Fischer Bosch Inst Clin Pharmacol, Stuttgart, Germany
[64]
Univ Washington, Sch Publ Hlth, Dept Epidemiol, Seattle, WA 98195 USA
[65]
Karolinska Inst, Dept Oncol Pathol, Stockholm, Sweden
[66]
BC Canc Agcy, Canc Control Res, Vancouver, BC, Canada
[67]
Antoni van Leeuwenhoek Hosp, Netherlands Canc Inst, Div Mol Pathol, Amsterdam, Netherlands
[68]
Vrije Univ Amsterdam Med Ctr, Dept Clin Genet, Amsterdam, Netherlands
[69]
Leiden Univ, Dept Pathol, Med Ctr, Leiden, Netherlands
[70]
Friedrich Alexander Univ Erlangen Nuremberg, Univ Hosp Erlangen, Comprehens Canc Ctr Erlangen EMN
[71]
Univ Sydney, Westmead Inst Med Res, Sydney, NSW, Australia
[72]
Univ Calif Irvine, Dept Epidemiol, Irvine, CA USA
[73]
Spanish Natl Canc Res Ctr, Human Canc Genet Program, Madrid, Spain
[74]
Xerencia Xest Integrada Vigo SERGAS, Inst Invest Biomed Galicia IISGS, Oncol & Genet Unit, Vigo
[75]
Canc Prevent Inst Calif, Dept Epidemiol, Fremont, CA USA
[76]
Univ Calif San Francisco, Dept Med, Inst Human Genet, Helen Diller Family Comprehens Canc Ctr, San
[77]
Univ Helsinki, Helsinki Univ Hosp, Dept Oncol, Helsinki, Finland
[78]
McGill Univ, Dept Med, Montreal, PQ, Canada
[79]
Radiumhosp, Oslo Univ Hosp, Inst Canc Res, Dept Canc Genet, Oslo, Norway
[80]
Tech Univ Munich, Div Gynaecol & Obstet, Munich, Germany
[81]
Univ Southampton, Southampton Clin Trials Unit, Southampton, Hants, England
[82]
Heidelberg Univ, Dept Obstet & Gynecol, Heidelberg, Germany
[83]
Univ Cambridge, Dept Publ Hlth & Primary Care, Ctr Canc Genet Epidemiol, Cambridge, England
[84]
Univ Florida, Dept Epidemiol, Gainesville, FL USA
[85]
Univ Laval, Res Ctr, Ctr Hosp Univ Quebec, Genom Ctr, Quebec City, PQ, Canada
[86]
Mayo Clin, Dept Hlth Sci Res, Rochester, MN USA
[87]
Erasmus Univ, Dept Clin Genet, Med Ctr, Rotterdam, Netherlands
[88]
Johns Hopkins Univ, Sch Med, Inst Med Genet, CIDR, Baltimore, MD USA
[89]
QIMR Berghofer Med Res Inst, Canc Div, Brisbane, Qld, Australia
[90]
Univ Oulu, Bioctr Oulu, Canc & Translat Med Res Unit, Lab Canc Genet & Tumor Biol, Oulu, Finland
[91]
Harvard TH Chan Sch Publ Hlth, Program Genet Epidemiol & Stat Genet, Boston, MA USA
[92]
Univ Utah, Sch Med, Huntsman Canc Inst, Dept Dermatol, Salt Lake City, UT USA
[93]
FIRC Italian Fdn Canc Res, Inst Mol Oncol, Milan, Italy
[94]
Inst Canc Res, Sect Canc Genet, London, England
[95]
Technion Israel Inst Technol, Ruth & Bruce Rappaport Fac Med, Carmel Med Ctr, Dept Community Med &
[96]
Univ Westminster, Fac Sci & Technol, Dept Biomed Sci, London, England
[97]
Univ Med Ctr Hamburg Eppendorf, Univ Canc Ctr Hamburg UCCH, Hamburg, Germany
[98]
Univ Sheffield, Sheffield Inst Nucle Acids, Dept Oncol & Metab, Sheffield, S Yorkshire, England
[99]
Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Los Angeles, CA USA
[100]
Univ Paris Saclay, Univ Paris Sud, INSERM, Canc & Environm Grp,Ctr Res Epidemiol & Populat H
[101]
Frederick Natl Lab Canc Res, Leidos Biomed Res, Canc Genom Res Lab, Frederick, MD USA
[102]
Kings Coll London, Guys Hosp, Res Oncol, London, England
[103]
Russian Acad Sci, Ufa Sci Ctr, Inst Biochem & Genet, Ufa, Russia
[104]
Univ Melbourne, Melbourne Sch Populat & Global Hlth, Ctr Epidemiol & Biostat, Melbourne, Vic
[105]
Natl Univ Ireland, Sch Med, Galway, Ireland
[106]
Pomeranian Med Univ, Dept Genet & Pathol, Szczecin, Poland
[107]
UCL, Inst Womens Hlth, Womens Canc, Gynaecol Canc Res Ctr, London, England
[108]
German Canc Res Ctr, Div Clin Epidemiol & Aging Res, Heidelberg, Germany
[109]
发布时间
2019-01-13
- 浏览3
Nature Genetics
Nature Genetics
968-978页
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