New neutralizing antibody epitopes in hepatitis C virus envelope glycoproteins are revealed by dissecting peptide recognition profiles.

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作者： Kachko, A. ^[1] ; Kochneva, G. ^[2] ; Sivolobova, G. ^[3] ; Grazhdantseva, A. ^[4] ; Lupan, T. ; Zubkova, I. ; Wells, F. ; Merchlinsky, M. ; Williams, O. ; Watanabe, H. ; Ivanova, A. ; Shvalov, A. ; Loktev, V. ; Netesov, S. ; Major, M. E.

作者单位： Yamagata University School of Medicine, Department of Gastroenterology, 2-2-2 Iida-nishi, Yamagata 990-9585, Japan ^[1] Laboratory of DNA Viruses, Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA ^[2] Laboratory of Hepatitis Viruses, Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA ^[3] Laboratory of Viral Hepatitis, State Research Center of Virology and Biotechnology “VECTOR”, Koltsovo, Novosibirsk 630559, Russian Federation ^[4]

关键词 Vaccine Cross neutralization Binding affinity Antibody blocking Antibody purification

发布时间 2020-09-08

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