MT5-MMP is a new pro-amyloidogenic proteinase that promotes amyloid pathology and cognitive decline in a transgenic mouse model of Alzheimer's disease

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作者： Baranger, Kevin ^[1] ; Marchalant, Yannick ^[2] ; Bonnet, Amandine E. ^[2] ; Crouzin, Nadine ^[2] ; Carrete, Alex ^[2] ; Paumier, Jean-Michel ^[2] ; Py, Nathalie A. ^[3] ; Bernard, Anne ^[4] ; Bauer, Charlotte ^[2] ; Charrat, Eliane ^[1] ; Moschke, Katrin ^[5] ; Seiki, Mothoharu ^[2] ; Vignes, Michel ^[2] ; Lichtenthaler, Stefan F. ^[5] ; Checler, Frederic ^[2] ; Khrestchatisky, Michel ^[2] ; Rivera, Santiago ^[2]

作者单位： IPMC UMR 7275 CNRS UNS, Labex DistAlz, F-06560 Valbonne, France ^[1] Aix Marseille Univ, CNRS, NICN UMR 7259, F-13344 Marseille, France ^[2] Univ Montpellier I, IBMM CNRS UMR5247, F-34095 Montpellier, France ^[3] Univ Tokyo, Inst Med Sci, Div Canc Cell Res, Minato Ku, Tokyo 1088639, Japan ^[4] German Ctr Neurodegenerat Dis DZNE & Neuroprote, Munich, Germany ^[5]

关键词 MMP-24 Synaptotoxicity Neuroprotection Knockout mouse Neurodegenerative disease

发布时间 2016-04-19

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