Exploiting transport activity of P-glycoprotein at the blood-brain barrier for the development of peripheral cannabinoid type 1 receptor antagonists

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作者： Wittgen,H.G.M. ^[1] ; Greupink,R. ^[2] ; VanDenHeuvel,J.J.M.W. ; VanDenBroek,P.H.H. ; Dinter-Heidorn,H. ; Koenderink,J.B. ; Russel,F.G.M.

作者单位： Abbott Products GmbH, Hannover, Germany ^[1] Department of Pharmacology and Toxicology, Radboud University Nijmegen Medical Centre, Nijmegen ^[2]

关键词 active transport baculovirus blood-brain barrier brain/plasma ratio breast cancer resistance protein cellular accumulation assay P-glycoprotein peripheral CB1 receptor antagonist

发布时间 2013-11-20

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Molecular pharmaceutics

2012年9卷5期

1351-1360页

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Exploiting transport activity of P-glycoprotein at the blood-brain barrier for the development of peripheral cannabinoid type 1 receptor antagonists

Molecular pharmaceutics

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Molecular pharmaceutics

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Exploiting transport activity of P-glycoprotein at the blood-brain barrier for the development of peripheral cannabinoid type 1 receptor antagonists

Molecular pharmaceutics

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Molecular pharmaceutics

相关期刊

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