Isotope dilution LC-MS/MS quantification of the cystic fibrosis transmembrane conductance regulator (CFTR) modulators ivacaftor, lumacaftor, tezacaftor, elexacaftor, and their major metabolites in human serum-论文-万方医学网

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Isotope dilution LC-MS/MS quantification of the cystic fibrosis transmembrane conductance regulator (CFTR) modulators ivacaftor, lumacaftor, tezacaftor, elexacaftor, and their major metabolites in human serum

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第一作者： Katharina,Habler

作者： Katharina,Habler ^[1] ; Anne-Sophie,Kalla ^[2] ; Michael,Rychlik ^[3] ; Mathias,Bruegel ; Daniel,Teupser ; Susanne,N?hrig ; Michael,Vogeser ; Michael,Paal

作者单位： Institute of Laboratory Medicine, University Hospital, LMU Munich ^[1] Chair of Analytical Food Chemistry, Technical University of Munich ^[2] Department of Medicine V ^[3]

关键词 cystic fibrosis (CF)cystic fibrosis transmembrane conductance regulator (CFTR) modulators isotope dilution liquid chromatography tandem mass spectrometry (ID-LC-MS/MS)therapeutic drug monitoring (TDM)

发布时间 2022-08-26

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Isotope dilution LC-MS/MS quantification of the cystic fibrosis transmembrane conductance regulator (CFTR) modulators ivacaftor, lumacaftor, tezacaftor, elexacaftor, and their major metabolites in human serum

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Isotope dilution LC-MS/MS quantification of the cystic fibrosis transmembrane conductance regulator (CFTR) modulators ivacaftor, lumacaftor, tezacaftor, elexacaftor, and their major metabolites in human serum

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