Optimization of CRISPR/Cas9 Technology to Knock Out Genes of Interest in Aneuploid Cell Lines

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作者： Dyikanov, Daniyar T. ^[1] ; Vasiluev, Petr A. ^[2] ; Rysenkova, Karina D. ^[3] ; Aleksandrushkina, Natalia A. ^[4] ; Tyurin-Kuzmin, Pyotr A. ; Kulebyakin, Konstantin Y. ; Rubtsov, Yury P. ; Shmakova, Anna A. ; Evseeva, Maria N. ; Balatskiy, Alexander V. ; Semina, Ekaterina V. ; Rostovtseva, Alexandra I. ; Makarevich, Pavel I. ; Karagyaur, Maxim N.

作者单位： Russian Acad Sci, Shemyakin Ovchinnikov Inst Bioorgan Chem, Moscow, Russia ^[1] Lomonosov Moscow State Univ, Med Res & Educ Ctr, Inst Regenerat Med, Lomonosov Ave,27,B-10, Moscow ^[2] Russian Acad Sci, Inst Gene Biol, FGBI Sci, Moscow, Russia ^[3] Lomonosov Moscow State Univ, Fac Med, Moscow, Russia ^[4]

关键词 genome editing CRISP Cas9 heterogeneous cell culture clone effect cell model off-targets

发布时间 2019-10-15

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