换一批Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
作者：
Sims, Rebecca [1]
;
van der Lee, Sven J. [2]
;
Naj, Adam C. [3]
;
Bellenguez, Celine [4]
;
Badarinarayan, Nandini [5]
;
Jakobsdottir, Johanna [6]
;
Kunkle, Brian W. [7]
;
Boland, Anne [8]
;
Raybould, Rachel [9]
;
Bis, Joshua C. [10]
;
Martin, Eden R. [11]
;
Grenier-Boley, Benjamin [12]
;
Heilmann-Heimbach, Stefanie [13]
;
Chouraki, Vincent [14]
;
Kuzma, Amanda B. [15]
;
Sleegers, Kristel [16]
;
Vronskaya, Maria [17]
;
Ruiz, Agustin [18]
;
Graham, Robert R. [19]
;
Olaso, Robert [20]
;
Hoffmann, Per [21]
;
Grove, Megan L. [22]
;
Vardarajan, Badri N. [23]
;
Hiltunen, Mikko [24]
;
Noethen, Markus M. [25]
;
White, Charles C. [26]
;
Hamilton-Nelson, Kara L. [27]
;
Epelbaum, Jacques [28]
;
Maier, Wolfgang [29]
;
Choi, Seung-Hoan [30]
;
Beecham, Gary W. [31]
;
Dulary, Cecile [32]
;
Herms, Stefan [33]
;
Smith, Albert V. [34]
;
Funk, Cory C. [35]
;
Derbois, Celine [36]
;
Forstner, Andreas J. [37]
;
Ahmad, Shahzad [38]
;
Li, Hongdong [39]
;
Bacq, Delphine [40]
;
Harold, Denise [41]
;
Satizabal, Claudia L. [42]
;
Valladares, Otto [43]
;
Squassina, Alessio [44]
;
Thomas, Rhodri [45]
;
Brody, Jennifer A. [46]
;
Qu, Liming [47]
;
Sanchez-Juan, Pascual [48]
;
Morgan, Taniesha [49]
;
Wolters, Frank J. [50]
;
Zhao, Yi [51]
;
Sanchez Garcia, Florentino [52]
;
Denning, Nicola [53]
;
Fornage, Myriam [54]
;
Malamon, John [55]
;
Deniz Naranjo, Maria Candida [56]
;
Majounie, Elisa [57]
;
Mosley, Thomas H. [58]
;
Dombroski, Beth [59]
;
Wallon, David [60]
;
Lupton, Michelle K. [61]
;
Dupuis, Josee [62]
;
Whitehead, Patrice [63]
;
Fratiglioni, Laura [64]
;
Medway, Christopher [65]
;
Jian, Xueqiu [66]
;
Mukherjee, Shubhabrata [67]
;
Keller, Lina [68]
;
Brown, Kristelle [69]
;
Lin, Honghuang [70]
;
Cantwell, Laura B. [71]
;
Panza, Francesco [72]
;
McGuinness, Bernadette [73]
;
Moreno-Grau, Sonia [74]
;
Burgess, Jeremy D. [75]
;
Solfrizzi, Vincenzo [76]
;
Proitsi, Petra [77]
;
Adams, Hieab H. [78]
;
Allen, Mariet [79]
;
Seripa, Davide [80]
;
Pastor, Pau [81]
;
Cupples, L. Adrienne [82]
;
Price, Nathan D. [83]
;
Hannequin, Didier [84]
;
Frank-Garcia, Ana [85]
;
Levy, Daniel [86]
;
Chakrabarty, Paramita [87]
;
Caffarra, Paolo [88]
;
Giegling, Ina [89]
;
Beiser, Alexa S. [90]
;
Giedraitis, Vilmantas [91]
;
Hampel, Harald [92]
;
Garcia, Melissa E. [93]
;
Wang, Xue [94]
;
Lannfelt, Lars [95]
;
Mecocci, Patrizia [96]
;
Eiriksdottir, Gudny [97]
;
Crane, Paul K. [98]
;
Pasquier, Florence [99]
;
Boccardi, Virginia [100]
;
Henandez, Isabel [101]
;
Barber, Robert C. [102]
;
Scherer, Martin [103]
;
Tarraga, Lluis [104]
;
Adams, Perrie M. [105]
;
Leber, Markus [106]
;
Chen, Yuning [107]
;
Albert, Marilyn S. [108]
;
Riedel-Heller, Steffi [109]
;
Emilsson, Valur [110]
;
Beekly, Duane [111]
;
Braae, Anne [112]
;
Schmidt, Reinhold [113]
;
Blacker, Deborah [114]
;
Masullo, Carlo [115]
;
Schmidt, Helena [116]
;
Doody, Rachelle S. [117]
;
Spalletta, Gianfranco [118]
;
Longstreth, W. T., Jr. [119]
;
Fairchild, Thomas J. [120]
;
Bossu, Paola [121]
;
Lopez, Oscar L. [122]
;
Frosch, Matthew P. [123]
;
Sacchinelli, Eleonora [124]
;
Ghetti, Bernardino [125]
;
Yang, Qiong [126]
;
Huebinger, Ryan M. [127]
;
Jessen, Frank [128]
;
Li, Shuo [129]
;
Kamboh, M. Ilyas [130]
;
Morris, John [131]
;
Sotolongo-Grau, Oscar [132]
;
Katz, Mindy J. [133]
;
Corcoran, Chris [134]
;
Dunstan, Melanie [135]
;
Braddel, Amy [136]
;
Thomas, Charlene [137]
;
Meggy, Alun [138]
;
Marshall, Rachel [139]
;
Gerrish, Amy [140]
;
Chapman, Jade [141]
;
Aguilar, Miquel [142]
;
Taylor, Sarah [143]
;
Hill, Matt [144]
;
Diez Fairen, Mnica [145]
;
Hodges, Angela [146]
;
Vellas, Bruno [147]
;
Soininen, Hilkka [148]
;
Kloszewska, Iwona [149]
;
Daniilidou, Makrina [150]
;
Uphill, James [151]
;
Patel, Yogen [152]
;
Hughes, Joseph T. [153]
;
Lord, Jenny [154]
;
Turton, James [155]
;
Hartmann, Annette M. [156]
;
Cecchetti, Roberta [157]
;
Fenoglio, Chiara [158]
;
Serpente, Maria [159]
;
Arcaro, Marina [160]
;
Caltagirone, Carlo [161]
;
Orfei, Maria Donata [162]
;
Ciaramella, Antonio [163]
;
Pichler, Sabrina [164]
;
Mayhaus, Manuel [165]
;
Gu, Wei [166]
;
Lleo, Alberto [167]
;
Forte, Juan [168]
;
Blesa, Rafael [169]
;
Barber, Imelda S. [170]
;
Brookes, Keeley [171]
;
Cupidi, Chiara [172]
;
Maletta, Raffaele Giovanni [173]
;
Carrell, David [174]
;
Sorbi, Sandro [175]
;
Moebus, Susanne [176]
;
Urbano, Maria [177]
;
Pilotto, Alberto [178]
;
Kornhuber, Johannes [179]
;
Bosco, Paolo [180]
;
Todd, Stephen [181]
;
Craig, David [182]
;
Johnston, Janet [183]
;
Gill, Michael [184]
;
Lawlor, Brian [185]
;
Lynch, Aoibhinn [186]
;
Fox, Nick C. [187]
;
Hardy, John [188]
;
Albin, Roger L. [189]
;
Apostolova, Liana G. [190]
;
Arnold, Steven E. [191]
;
Asthana, Sanjay [192]
;
Atwood, Craig S. [193]
;
Baldwin, Clinton T. [194]
;
Barnes, Lisa L. [195]
;
Barral, Sandra [196]
;
Beach, Thomas G. [197]
;
Becker, James T. [198]
;
Bigio, Eileen H. [199]
;
Bird, Thomas D. [200]
;
Boeve, Bradley F. [201]
;
Bowen, James D. [202]
;
Boxer, Adam [203]
;
Burke, James R. [204]
;
Burns, Jeffrey M. [205]
;
Buxbaum, Joseph D. ;
Cairns, Nigel J. ;
Cao, Chuanhai ;
Carlson, Chris S. ;
Carlsson, Cynthia M. ;
Carney, Regina M. ;
Carrasquillo, Minerva M. ;
Carroll, Steven L. ;
Diaz, Carolina Ceballos ;
Chui, Helena C. ;
Clark, David G. ;
Cribbs, David H. ;
Crocco, Elizabeth A. ;
DeCarli, Charles ;
Dick, Malcolm ;
Duara, Ranjan ;
Evans, Denis A. ;
Faber, Kelley M. ;
Fallon, Kenneth B. ;
Fardo, David W. ;
Farlow, Martin R. ;
Ferris, Steven ;
Foroud, Tatiana M. ;
Galasko, Douglas R. ;
Gearing, Marla ;
Geschwind, Daniel H. ;
Gilbert, John R. ;
Graff-Radford, Neill R. ;
Green, Robert C. ;
Growdon, John H. ;
Hamilton, Ronald L. ;
Harrell, Lindy E. ;
Honig, Lawrence S. ;
Huentelman, Matthew J. ;
Hulette, Christine M. ;
Hyman, Bradley T. ;
Jarvik, Gail P. ;
Abner, Erin ;
Jin, Lee-Way ;
Jun, Gyungah ;
Karydas, Anna ;
Kaye, Jeffrey A. ;
Kim, Ronald ;
Kowall, Neil W. ;
Kramer, Joel H. ;
LaFerla, Frank M. ;
Lah, James J. ;
Leverenz, James B. ;
Levey, Allan I. ;
Li, Ge ;
Lieberman, Andrew P. ;
Lunetta, Kathryn L. ;
Lyketsos, Constantine G. ;
Marson, Daniel C. ;
Martiniuk, Frank ;
Mash, Deborah C. ;
Masliah, Eliezer ;
McCormick, Wayne C. ;
McCurry, Susan M. ;
McDavid, Andrew N. ;
Mckee, Ann C. ;
Mesulam, Marsel ;
Miller, Bruce L. ;
Miller, Carol A. ;
Miller, Joshua W. ;
Morris, John C. ;
Murrell, Jill R. ;
Myers, Amanda J. ;
O'Bryant, Sid ;
Pankratz, Vernon S. ;
Parisi, Joseph E. ;
Paulson, Henry L. ;
Perry, William ;
Peskind, Elaine ;
Pierce, Aimee ;
Poon, Wayne W. ;
Potter, Huntington ;
Quinn, Joseph F. ;
Raj, Ashok ;
Raskind, Murray ;
Reisberg, Barry ;
Reitz, Christiane ;
Ringman, John M. ;
Roberson, Erik D. ;
Rogaeva, Ekaterina ;
Rosen, Howard J. ;
Rosenberg, Roger N. ;
Sager, Mark A. ;
Saykin, Andrew J. ;
Schneider, Julie A. ;
Schneider, Lon S. ;
Seeley, William W. ;
Smith, Amanda G. ;
Sonnen, Joshua A. ;
Spina, Salvatore ;
Stern, Robert A. ;
Swerdlow, Russell H. ;
Tanzi, Rudolph E. ;
Thornton-Wells, Tricia A. ;
Trojanowski, John Q. ;
Troncoso, Juan C. ;
Van Deerlin, Vivianna M. ;
Van Eldik, Linda J. ;
Vinters, Harry V. ;
Vonsattel, Jean Paul ;
Weintraub, Sandra ;
Welsh-Bohmer, Kathleen A. ;
Wilhelmsen, Kirk C. ;
Williamson, Jennifer ;
Woltjer, Randall L. ;
Wright, Clinton B. ;
Yu, Chang-En ;
Yu, Lei ;
Garzia, Fabienne ;
Golamaully, Feroze ;
Septier, Gislain ;
Engelborghs, Sebastien ;
Vandenberghe, Rik ;
De Deyn, Peter P. ;
Munoz Fernadez, Carmen ;
Aladro Benito, Yoland ;
Thonberg, Hakan ;
Forsell, Charlotte ;
Lilius, Lena ;
Kinhult-Stahlbom, Anne ;
Kilander, Lena ;
Brundin, RoseMarie ;
Concari, Letizia ;
Helisalmi, Seppo ;
Koivisto, Anne Maria ;
Haapasalo, Annakaisa ;
Dermecourt, Vincent ;
Fievet, Nathalie ;
Hanon, Olivier ;
Dufouil, Carole ;
Brice, Alexis ;
Ritchie, Karen ;
Dubois, Bruno ;
Himali, Jayanadra J. ;
Keene, C. Dirk ;
Tschanz, Joann ;
Fitzpatrick, Annette L. ;
Kukull, Walter A. ;
Norton, Maria ;
Aspelund, Thor ;
Larson, Eric B. ;
Munger, Ron ;
Rotter, Jerome I. ;
Lipton, Richard B. ;
Bullido, Maria J. ;
Hofman, Albert ;
Montine, Thomas J. ;
Coto, Eliecer ;
Boerwinkle, Eric ;
Petersen, Ronald C. ;
Alvarez, Victoria ;
Rivadeneira, Fernando ;
Reiman, Eric M. ;
Gallo, Maura ;
O'Donnell, Christopher J. ;
Reisch, Joan S. ;
Bruni, Amalia Cecilia ;
Royall, Donald R. ;
Dichgans, Martin ;
Sano, Mary ;
Galimberti, Daniela ;
St George-Hyslop, Peter ;
Scarpini, Elio ;
Tsuang, Debby W. ;
Mancuso, Michelangelo ;
Bonuccelli, Ubaldo ;
Winslow, Ashley R. ;
Daniele, Antonio ;
Wu, Chuang-Kuo ;
Peters, Oliver ;
Nacmias, Benedetta ;
Riemenschneider, Matthias ;
Heun, Reinhard ;
Brayne, Carol ;
Rubinsztein, David C. ;
Bras, Jose ;
Guerreiro, Rita ;
Al-Chalabi, Ammar ;
Shaw, Christopher E. ;
Collinge, John ;
Mann, David ;
Tsolaki, Magda ;
Clarimon, Jordi ;
Sussams, Rebecca ;
Lovestone, Simon ;
O'Donovan, Michael C. ;
Owen, Michael J. ;
Behrens, Timothy W. ;
Mead, Simon ;
Goate, Alison M. ;
Uitterlinden, Andre G. ;
Holmes, Clive ;
Cruchaga, Carlos ;
Ingelsson, Martin ;
Bennett, David A. ;
Powell, John ;
Golde, Todd E. ;
Graff, Caroline ;
De Jager, Philip L. ;
Morgan, Kevin ;
Ertekin-Taner, Nilufer ;
Combarros, Onofre ;
Psaty, Bruce M. ;
Passmore, Peter ;
Younkin, Steven G. ;
Berr, Claudine ;
Gudnason, Vilmundur ;
Rujescu, Dan ;
Dickson, Dennis W. ;
Dartigues, Jean-Francois ;
DeStefano, Anita L. ;
Ortega-Cubero, Sara ;
Hakonarson, Hakon ;
Campion, Dominique ;
Boada, Merce ;
Kauwe, John Keoni ;
Farrer, Lindsay A. ;
Van Broeckhoven, Christine ;
Ikram, M. Arfan ;
Jones, Lesley ;
Haines, Jonathan L. ;
Tzourio, Christophe ;
Launer, Lenore J. ;
Escott-Price, Valentina ;
Mayeux-, Richard ;
Deleuze, Jean-Francois ;
Amin, Najaf ;
Holmans, Peter A. ;
Pericak-Vance, Margaret A. ;
Amouyel, Philippe ;
van Duijn, Cornelia M. ;
Ramirez, Alfredo ;
Wang, Li-San ;
Lambert, Jean-Charles ;
Seshadri, Sudha ;
Williams, Julie ;
Schellenberg, Gerard D.
作者单位：
Univ Texas Hlth Sci Ctr San Antonio, Dept Psychiat, San Antonio, TX 78229 USA
[1]
Univ Eastern Finland, Inst Biomed, Kuopio, Finland
[2]
Univ Washington, Dept Neurol, Seattle, WA 98195 USA
[3]
Univ Calif Davis, Dept Neurol, Sacramento, CA 95817 USA
[4]
Boston Univ, Dept Neurol, Boston, MA USA
[5]
Univ Miami, Dept Neurol, Miami, FL USA
[6]
Neurol Serv, Santander, Spain
[7]
Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10467 USA
[8]
Ctr Hosp Univ Lille, Epidemiol & Publ Hlth Dept, Lille, France
[9]
Univ Hosp, Dept Psychiat & Psychotherapy, Saarland, Germany
[10]
Univ Paris 06, UPMC, Sorbonne Univ,CNRS,UMR 7225,UMRS 1127, Inst Cerveau & Moelle Epinisre,INSERM
[11]
Univ Washington, Natl Alzheimers Coordinating Ctr, Seattle, WA 98195 USA
[12]
Charite, Dept Psychiat, Berlin, Germany
[13]
Harvard Sch Publ Hlth, Dept Epidemiol, Boston, MA USA
[14]
Univ Kentucky, Sanders Brown Ctr Aging, Dept Biostat, Lexington, KY 40536 USA
[15]
Univ Calif Irvine, Dept Neurobiol & Behav, Irvine, CA USA
[16]
UCL Inst Neurol, MRC Prion Unit, Dept Neurodegenerat Dis, London, England
[17]
Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA
[18]
Framingham Heart Dis Epidemiol Study, Framingham, MA USA
[19]
Univ Paris 05, INSERM, Ctr Psychiat & Neurosci, UMR 894, Paris, France
[20]
Med Univ Graz, Inst Mol Biol & Biochem, Graz, Austria
[21]
Dublin City Univ, Sch Biotechnol, Dublin, Ireland
[22]
Harvard Med Sch, Massachusetts Gen Hosp, Dept Neurol, Boston, MA USA
[23]
Mayo Clin, Dept Neurol, Rochester, MN USA
[24]
Columbia Univ, Dept Neurol, Med Ctr, Ctr Translat & Syst Neuroimmunol, New York, NY USA
[25]
Massachusetts Gen Hosp, CS Kubik Lab Neuropathol, Charlestown, MA USA
[26]
Kings Coll London, Inst Psychiat Psychol & Neurosci, London, England
[27]
Univ Erlangen Nurnberg, Dept Psychiat & Psychotherapy, Erlangen, Germany
[28]
Med Univ Lodz, Elderly & Psychiat Disorders Dept, Lodz, Poland
[29]
Klinikum Univ Munchen, Inst Stroke & Dementia Res, Munich, Germany
[30]
VIB, Dept Mol Genet, Neurodegenerat Brain Dis Grp, Antwerp, Belgium
[31]
Univ Bonn, Dept Psychiat & Psychotherapy, Bonn, Germany
[32]
Translat Genom Res Inst, Neurogenom Div, Phoenix, AZ USA
[33]
Univ Kentucky, Sanders Brown Ctr Aging, Coll Publ Hlth, Dept Epidemiol, Lexington, KY 40536 USA
[34]
Univ Kentucky, Sanders Brown Ctr Aging, Dept Anat & Neurobiol, Lexington, KY 40536 USA
[35]
Univ Parma, Dept Neurosci, Parma, Italy
[36]
Univ Nottingham, Sch Life Sci, Nottingham, England
[37]
Univ Cagliari, Dept Biomed Sci, Sect Neurosci & Clin Pharmacol, Cagliari, Italy
[38]
Univ Southern Calif, Dept Pathol, Los Angeles, CA 90089 USA
[39]
Kuopio Univ Hosp, Dept Neurol, Kuopio, Finland
[40]
Univ North Carolina Chapel Hill, Dept Genet, Chapel Hill, NC USA
[41]
Martin Luther Univ Halle Wittenberg, Dept Psychiat, Halle, Germany
[42]
Univ Cent Asturias, Mol Genet Lab Hosp, Oviedo, Spain
[43]
Inst Invest Sanitaria Hosp la Paz IdiPAZ, Madrid, Spain
[44]
Univ Calif Los Angeles, Dept Neurol, Los Angeles, CA 90024 USA
[45]
NIA, Lab Epidemiol & Populat Sci, Bethesda, MD 20892 USA
[46]
Univ Perugia, Dept Med, Sect Gerontol & Geriatr, Perugia, Italy
[47]
IRCCS, Santa Lucia Fdn, Expt Neuropsychiat Lab, Dept Clin & Behav Neurol, Rome, Italy
[48]
Univ Cologne, Dept Psychiat & Psychotherapy, Cologne, Germany
[49]
Banner Sun Hlth Res Inst, Civin Lab Neuropathol, Phoenix, AZ USA
[50]
Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Basic & Clin Neurosci, London, England
[51]
Univ Calif San Diego, Dept Neurosci, La Jolla, CA 92093 USA
[52]
Iceland Heart Assoc, Kopavogur, Iceland
[53]
Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA
[54]
CMRR Bordeaux, Memory Res & Resources Ctr, Bordeaux, France
[55]
Univ Texas Southwestern Med Ctr Dallas, Dept Psychiat, Dallas, TX USA
[56]
Univ Penn, Dept Psychiat, Perelman Sch Med, Philadelphia, PA 19104 USA
[57]
Boston Univ, Dept Biostat, Boston, MA 02215 USA
[58]
Univ Calif Irvine, Dept Pathol & Lab Med, Irvine, CA USA
[59]
La Colombiere Hosp, INSERM, U1061, Montpellier, France
[60]
Brigham Young Univ, Dept Biol, Provo, UT 84602 USA
[61]
IRCCS Casa Sollievo Sofferenza, Geriatr Unit, San Giovanni Rotondo, Italy
[62]
Univ Calif Davis, Dept Pathol & Lab Med, Sacramento, CA 95817 USA
[63]
Johns Hopkins Univ, Dept Psychiat, Baltimore, MD USA
[64]
Univ Pittsburgh, Dept Psychiat, Pittsburgh, PA USA
[65]
Ctr Natl Genotypage, Inst Genom, CEA, Evry, France
[66]
Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands
[67]
Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Old Age Psychiat, London, England
[68]
Univ Med Ctr Hamburg Eppendorf, Dept Primary Med Care, Hamburg, Germany
[69]
Univ Texas Southwestern Med Ctr Dallas, Dept Surg, Dallas, TX USA
[70]
Inst Catala Neurociencies Aplicades, Res Ctr, Barcelona, Spain
[71]
Univ Calif Los Angeles, Neurogenet Program, Los Angeles, CA USA
[72]
Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam
[73]
Indiana Univ, Dept Med & Mol Genet, Indianapolis, IN USA
[74]
Northwestern Univ, Feinberg Sch Med, Dept Pathol, Chicago, IL 60611 USA
[75]
Karolinska Univ, Hosp Huddinge, Genet Unit, Dept Geriatr Med, Stockholm, Sweden
[76]
Univ Calif San Francisco, Dept Neuropsychol, San Francisco, CA 94143 USA
[77]
Duke Univ, Dept Pathol, Durham, NC 27706 USA
[78]
Boston Univ, Sch Med, Dept Med, Sect Computat Biomed, Boston, MA 02118 USA
[79]
Genentech Inc, Immunol Biomarkers Grp, San Francisco, CA USA
[80]
Univ S Florida, USF Hlth Byrd Alzheimers Inst, Tampa, FL USA
[81]
Univ Calif San Francisco, Dept Neurol, San Francisco, CA USA
[82]
Washington Univ, Sch Med, Dept Psychiat, St Louis, MO 63110 USA
[83]
Univ Kansas, Med Ctr, Alzheimers Dis Ctr, Kansas City, KS 66103 USA
[84]
Hosp Univ Doctor Negrin, Dept Immunol, Las Palmas Gran Canaria, Spain
[85]
Univ Texas Southwestern Med Ctr Dallas, Dept Clin Sci, Dallas, TX 75390 USA
[86]
Washington Univ, Dept Pathol & Immunol, St Louis, MO USA
[87]
Univ Cambridge, Inst Publ Hlth, Cambridge, England
[88]
Hosp Network Antwerp, Dept Neurol, Antwerp, Belgium
[89]
Univ Leipzig, Inst Social Med Occupat Hlth & Publ Hlth, Leipzig, Germany
[90]
Univ Texas Hlth Sci Ctr Houston, Human Genet Ctr, Sch Publ Hlth, Houston, TX USA
[91]
Ctr Hos Rouvray, Sotteville Ies Rouen, France
[92]
Uppsala Univ, Dept Publ Hlth Geriatr, Uppsala, Sweden
[93]
Univ Wisconsin, GRECC, Madison, WI USA
[94]
Boston Univ, Sch Med, Boston, MA 02118 USA
[95]
Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain
[96]
Univ Southern Calif, Dept Neurol, Los Angeles, CA USA
[97]
Univ Autonoma Madrid, Univ Hosp La Paz, Dept Neurol, Madrid, Spain
[98]
Mt Sinai Sch Med, Dept Genet & Genom Sci, New York, NY USA
[99]
Univ Milan, IRCCS Osped Policlin, Fdn Ca Granda, Dept Pathophysiol & Transplantat, Milan, Italy
[100]
Mt Sinai Sch Med, Dept Psychiat, New York, NY USA
[101]
Case Western Reserve Univ, Dept Epidemiol & Biostat, Cleveland, OH 44106 USA
[102]
UCL, Inst Neurol, Dept Mol Neurosci, London, England
[103]
Univ Wisconsin, Dept Med, Madison, WI USA
[104]
Emory Univ, Dept Neurol, Atlanta, GA USA
[105]
Univ Florida, Dept Neurosci, Ctr Translat Res Neurodegenerat Dis, Gainesville, FL 32610 USA
[106]
Texas Tech Univ, Hlth Sci Ctr, Dept Neurol, Lubbock, TX 79430 USA
[107]
Karolinska Inst, Dept Neurobiol, Care Sci & Soc, Aging Res Ctr, Stockholm, Sweden
[108]
Univ North Texas, Hlth Sci Ctr, Div Geriatr, Internal Med, Ft Worth, TX USA
[109]
Harbor UCLA Med Ctr, Los Angeles BioMed Res Inst, Inst Translat Genom & Populat Sci, Torrance, CA
[110]
Univ Alabama Birmingham, Dept Neurol, Birmingham, AL USA
[111]
Univ Washington, Dept Pathol, Seattle, WA 98195 USA
[112]
Univ Calif Irvine, Inst Memory Impairments & Neurol Disorder, Irvine, CA USA
[113]
Columbia Univ, Dept Pathol, Taub Inst Alzheimers Dis & Aging Brain, New York, NY USA
[114]
Mt Sinai Sch Med, Dept Neurosci, New York, NY USA
[115]
Univ North Texas, Hlth Sci Ctr, Off Strategy & Measurement, Ft Worth, TX USA
[116]
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发布时间
2018-03-07
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Nature Genetics
Nature Genetics
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