Surface conjugation of EP67 to biodegradable nanoparticles increases the generation of long-lived mucosal and systemic memory T-cells by encapsulated protein vaccine after respiratory immunization and subsequent T-cell-mediated protection against respiratory infection

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作者： Tallapaka, Shailendra B. ^[1] ; Karuturi, Bala V. K. ^[2] ; Yeapuri, Pravin ^[3] ; Curran, Stephen M. ^[4] ; Sonawane, Yogesh A. ^[5] ; Phillips, Joy A. ^[6] ; Smith, D. David ^[7] ; Sanderson, Sam D. ; Vetro, Joseph A.

作者单位： Eppley Inst Res Canc & Allied Dis, Omaha, NE 68022 USA ^[1] Creighton Univ, Dept Biomed Sci, 2500 Calif Plaza, Omaha, NE 68178 USA ^[2] San Diego State Univ, Donald P Shiley BioSci Ctr, San Diego, CA 92115 USA ^[3] Mylan Pharmaceut Inc, 781 Chestnut Ridge Rd, Morgantown, WV 26505 USA ^[4] Univ Nebraska Med Ctr, Dept Pharmaceut Sci, Coll Pharm, 986025 Nebraska Med Ctr, Omaha, NE 68198 USA ^[5] DILIsym Serv Inc, Six Davis Dr,POB 12317, Res Triangle Pk, NC 27709 USA ^[6] Univ Nebraska Med Ctr, Ctr Drug Delivery & Nanomed, Coll Pharm, 986025 Nebraska Med Ctr, Omaha, NE ^[7]

关键词 Mucosal vaccine Vaccine delivery Nanoparticle Targeted vaccines Dendritic cell targeting CD88 Host-derived immunostimulant Complement-derived immunostimulant

发布时间 2019-11-13

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International Journal of Pharmaceutics

2019年565卷

242-257页

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Surface conjugation of EP67 to biodegradable nanoparticles increases the generation of long-lived mucosal and systemic memory T-cells by encapsulated protein vaccine after respiratory immunization and subsequent T-cell-mediated protection against respiratory infection

International Journal of Pharmaceutics

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International Journal of Pharmaceutics

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Surface conjugation of EP67 to biodegradable nanoparticles increases the generation of long-lived mucosal and systemic memory T-cells by encapsulated protein vaccine after respiratory immunization and subsequent T-cell-mediated protection against respiratory infection

International Journal of Pharmaceutics

相似文献

International Journal of Pharmaceutics

相关期刊

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