Synthesis, biological evaluation, and molecular modeling of abiraterone analogues: Novel CYP17 inhibitors for the treatment of prostate cancer

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作者： Mendieta MAEPB ^[1] ; Negri M ^[2] ; Jagusch C ^[3] ; Vieira UM ; Lauterbach T ; Hartmann RW

作者单位： Univ Saarland, D-66041 Saarbrucken, Germany ^[1] Schwarz Pharma AG, D-40789 Monheim, Germany ^[2] Pharmacelsus CRO, D-66123 Saarbrucken, Germany ^[3]

关键词 P450 17 C-17 C-20-LYASE INHIBITORS POTENTIAL THERAPEUTICS ANDROGEN RECEPTOR CYP-17 INHIBITORS HIGHLY POTENT IN-VIVO ENZYME 17-ALPHA-HYDROXYLASE KETOCONAZOLE

发布时间 2013-11-20

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Journal of Medicinal Chemistry

2008年51卷16期

5009-5018页

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Synthesis, biological evaluation, and molecular modeling of abiraterone analogues: Novel CYP17 inhibitors for the treatment of prostate cancer

Journal of Medicinal Chemistry

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Journal of Medicinal Chemistry

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Synthesis, biological evaluation, and molecular modeling of abiraterone analogues: Novel CYP17 inhibitors for the treatment of prostate cancer

Journal of Medicinal Chemistry

相似文献

Journal of Medicinal Chemistry

相关期刊

检索历史清除