Discovery and structure-activity relationship of 3-methoxy-N-(3-(1-methyl-1 H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide (APD791): A highly selective 5-hydroxytryptamine_(2A) receptor inverse agonist for the treatment of arterial thrombosis

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作者： Xiong, Y. ^[1] ; Teegarden, B.R. ; Choi, J.-S.K. ; Strah-Pleynet, S. ; Decaire, M. ; Jayakumar, H. ; Dosa, P.I. ; Casper, M.D. ; Pham, L. ; Feichtinger, K. ; Ullman, B. ; Adams, J. ; Yuskin, D. ; Frazer, J. ; Morgan, M. ; Sadeque, A. ; Chen, W. ; Webb, R.R. ; Connolly, D.T. ; Semple, G. ; Al-Shamma, H.

作者单位： Arena Pharmaceuticals, 6166 Nancy Ridge Drive, San Diego, CA 92121, United States ^[1]

发布时间 2013-11-20

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Journal of Medicinal Chemistry

2010年53卷11期

4412-4421页

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Discovery and structure-activity relationship of 3-methoxy-N-(3-(1-methyl-1 H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide (APD791): A highly selective 5-hydroxytryptamine_(2A) receptor inverse agonist for the treatment of arterial thrombosis

Journal of Medicinal Chemistry

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Discovery and structure-activity relationship of 3-methoxy-N-(3-(1-methyl-1 H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide (APD791): A highly selective 5-hydroxytryptamine_(2A) receptor inverse agonist for the treatment of arterial thrombosis

Journal of Medicinal Chemistry

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Journal of Medicinal Chemistry

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