Structural insights into the enhanced thermostability of cysteine substitution mutants of L-histidine decarboxylase from Photobacterium phosphoreum
第一作者:
Yuki,Oda
作者:
关键词
thermostable mutantthermostabilityprotein engineeringhistidine decarboxylasecrystal structureAbbreviations: AADCsamino acid decarboxylaseASAaccessible surface areaCLcatalytic loopHDCL-histidine decarboxylaseHDHhistamine dehydrogenaseHsHDCHDC from humansLLlong loop1-methoxy PMS1-methoxy-5-methylphenazinium methylsulfateMjTDCtyrosine decarboxylase from Methanocaldococcus jannaschiiMRmolecular replacementPLPpyridoxal 5′-phosphatePpHDCL-histidine decarboxylase from Photobacterium phosphoreumPpHDC-SMPpHDC C57S mutantPpHDC-TMPpHDC C57S/C101V/C282V mutant(WST)-8water-soluble tetrazolium saltWTwild-type
发布时间
2022-07-27
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