换一批Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates A beta, tau, immunity and lipid processing
第一作者：
Kunkle, Brian W.
作者：
Kunkle, Brian W. [1]
;
Grenier-Boley, Benjamin [2]
;
Sims, Rebecca [3]
;
Bis, Joshua C. [4]
;
Damotte, Vincent [5]
;
Naj, Adam C. [6]
;
Boland, Anne [7]
;
Vronskaya, Maria [8]
;
van der Lee, Sven J. [9]
;
Amlie-Wolf, Alexandre [10]
;
Bellenguez, Celine [11]
;
Frizatti, Aura [12]
;
Chouraki, Vincent [13]
;
Martin, Eden R. [14]
;
Sleegers, Kristel [15]
;
Badarinarayan, Nandini [16]
;
Jakobsdottir, Johanna [17]
;
Hamilton-Nelson, Kara L. [18]
;
Moreno-Grau, Sonia [19]
;
Olaso, Robert [20]
;
Raybould, Rachel [21]
;
Chen, Yuning [22]
;
Kuzma, Amanda B. [23]
;
Hiltunen, Mikko [24]
;
Morgan, Taniesha [25]
;
Ahmad, Shahzad [26]
;
Vardarajan, Badri N. [27]
;
Epelbaum, Jacques [28]
;
Hoffmann, Per [29]
;
Boada, Merce [30]
;
Beecham, Gary W. [31]
;
Garnier, Jean-Guillaume [32]
;
Harold, Denise [33]
;
Fitzpatrick, Annette L. [34]
;
Valladares, Otto [35]
;
Moutet, Marie-Laure [36]
;
Gerrish, Amy [37]
;
Smith, Albert, V [38]
;
Qu, Liming [39]
;
Bacq, Delphine [40]
;
Denning, Nicola [41]
;
Jian, Xueqiu [42]
;
Zhao, Yi [43]
;
Del Zompo, Maria [44]
;
Fox, Nick C. [45]
;
Choi, Seung-Hoan [46]
;
Mateo, Ignacio [47]
;
Hughes, Joseph T. [48]
;
Adams, Hieab H. [49]
;
Malamon, John [50]
;
Sanchez-Garcia, Florentino [51]
;
Patel, Yogen [52]
;
Brody, Jennifer A. [53]
;
Dombroski, Beth A. [54]
;
Naranjo, Maria Candida Deniz [55]
;
Daniilidou, Makrina [56]
;
Eiriksdottir, Gudny [57]
;
Mukherjee, Shubhabrata [58]
;
Wallon, David [59]
;
Uphill, James [60]
;
Aspelund, Thor [61]
;
Cantwell, Laura B. [62]
;
Garzia, Fabienne [63]
;
Galimberti, Daniela [64]
;
Hofer, Edith [65]
;
Butkiewicz, Mariusz [66]
;
Fin, Bertrand [67]
;
Scarpini, Elio [68]
;
Sarnowski, Chloe [69]
;
Bush, Will S. [70]
;
Meslage, Stphane [71]
;
Kornhuber, Johannes [72]
;
White, Charles C. [73]
;
Song, Yuenjoo [74]
;
Barber, Robert C. [75]
;
Engelborghs, Sebastiaan [76]
;
Sordon, Sabrina [77]
;
Voijnovic, Dina [78]
;
Adams, Perrie M. [79]
;
Vandenberghe, Rik [80]
;
Mayhaus, Manuel [81]
;
Cupples, L. Adrienne [82]
;
Albert, Marilyn S. [83]
;
De Deyn, Peter P. [84]
;
Gu, Wei [85]
;
Himali, Jayanadra J. [86]
;
Beekly, Duane [87]
;
Squassina, Alessio [88]
;
Hartmann, Annette M. [89]
;
Orellana, Adelina [90]
;
Blacker, Deborah [91]
;
Rodriguez-Rodriguez, Eloy [92]
;
Lovestone, Simon [93]
;
Garcia, Melissa E. [94]
;
Doody, Rachelle S. [95]
;
Munoz-Fernadez, Carmen [96]
;
Sussams, Rebecca [97]
;
Lin, Honghuang [98]
;
Fairchild, Thomas J. [99]
;
Benito, Yolanda A. [100]
;
Holmes, Clive [101]
;
Karamujic-Comic, Hata [102]
;
Frosch, Matthew P. [103]
;
Thonberg, Hakan [104]
;
Maier, Wolfgang [105]
;
Roschupkin, Gena [106]
;
Ghetti, Bernardino [107]
;
Giedraitis, Vilmantas [108]
;
Kawalia, Amit [109]
;
Li, Shuo [110]
;
Huebinger, Ryan M. [111]
;
Kilander, Lena [112]
;
Moebus, Susanne [113]
;
Hernandez, Isabel [114]
;
Kamboh, M. Ilyas [115]
;
Brundin, Rosemarie [116]
;
Turton, James [117]
;
Yang, Qiong [118]
;
Katz, Mindy J. [119]
;
Concari, Letizia [120]
;
Lord, Jenny [121]
;
Beiser, Alexa S. [122]
;
Keene, C. Dirk [123]
;
Helisalmi, Seppo [124]
;
Kloszewska, Iwona [125]
;
Kukull, Walter A. [126]
;
Koivisto, Anne Maria [127]
;
Lynch, Aoibhinn [128]
;
Tarraga, Lluis [129]
;
Larson, Eric B. [130]
;
Haapasalo, Annakaisa [131]
;
Lawlor, Brian [132]
;
Mosley, Thomas H. [133]
;
Lipton, Richard B. [134]
;
Solfrizzi, Vincenzo [135]
;
Gill, Michael [136]
;
Longstreth, W. T., Jr. [137]
;
Montine, Thomas J. [138]
;
Frisardi, Vincenza [139]
;
Diez-Fairen, Monica [140]
;
Rivadeneira, Fernando [141]
;
Petersen, Ronald C. [142]
;
Deramecourt, Vincent [143]
;
Alvarez, Ignacio [144]
;
Salani, Francesca [145]
;
Ciaramella, Antonio [146]
;
Boerwinkle, Eric [147]
;
Reiman, Eric M. [148]
;
Fievet, Nathalie [149]
;
Rotter, Jerome, I [150]
;
Reisch, Joan S. [151]
;
Hanon, Olivier [152]
;
Cupidi, Chiara [153]
;
Uitterlinden, A. G. Andre [154]
;
Royall, Donald R. [155]
;
Dufouil, Carole [156]
;
Maletta, Raffaele Giovanni [157]
;
de Rojas, Itziar [158]
;
Sano, Mary [159]
;
Brice, Alexis [160]
;
Cecchetti, Roberta [161]
;
St George-Hyslop, Peter [162]
;
Ritchie, Karen [163]
;
Tsolaki, Magda [164]
;
Tsuang, Debby W. [165]
;
Dubois, Bruno [166]
;
Craig, David [167]
;
Wu, Chuang-Kuo [168]
;
Soininen, Hilkka [169]
;
Avramidou, Despoina [170]
;
Albin, Roger L. [171]
;
Fratiglioni, Laura [172]
;
Germanou, Antonia [173]
;
Apostolova, Liana G. [174]
;
Keller, Lina [175]
;
Koutroumani, Maria [176]
;
Arnold, Steven E. [177]
;
Panza, Francesco [178]
;
Gkatzima, Olymbia [179]
;
Asthana, Sanjay [180]
;
Hannequin, Didier [181]
;
Whitehead, Patrice [182]
;
Atwood, Craig S. [183]
;
Caffarra, Paolo [184]
;
Hampel, Harald [185]
;
Quintela, Ines [186]
;
Carracedo, Angel [187]
;
Lannfelt, Lars [188]
;
Rubinsztein, David C. [189]
;
Barnes, Lisa L. [190]
;
Pasquier, Florence [191]
;
Froelich, Lutz [192]
;
Barral, Sandra [193]
;
McGuinness, Bernadette [194]
;
Beach, Thomas G. [195]
;
Johnston, Janet A. [196]
;
Becker, James T. [197]
;
Passmore, Peter [198]
;
Bigio, Eileen H. [199]
;
Schott, Jonathan M. [200]
;
Bird, Thomas D. [201]
;
Warren, Jason D. [202]
;
Boeve, Bradley F. [203]
;
Lupton, Michelle K. [204]
;
Bowen, James D. [205]
;
Proitsi, Petra [206]
;
Boxer, Adam [207]
;
Powell, John F. [208]
;
Burke, James R. [209]
;
Kauwe, John S. K. [210]
;
Burns, Jeffrey M. [211]
;
Mancuso, Michelangelo [212]
;
Buxbaum, Joseph D. [213]
;
Bonuccelli, Ubaldo [214]
;
Cairns, Nigel J. [215]
;
McQuillin, Andrew [216]
;
Cao, Chuanhai [217]
;
Livingston, Gill ;
Carlson, Chris S. ;
Bass, Nicholas J. ;
Carlsson, Cynthia M. ;
Hardy, John ;
Carney, Regina M. ;
Bras, Jose ;
Carrasquillo, Minerva M. ;
Guerreiro, Rita ;
Allen, Mariet ;
Chui, Helena C. ;
Fisher, Elizabeth ;
Masullo, Carlo ;
Crocco, Elizabeth A. ;
DeCarli, Charles ;
Bisceglio, Gina ;
Dick, Malcolm ;
Ma, Li ;
Duara, Ranjan ;
Graff-Radford, Neill R. ;
Evans, Denis A. ;
Hodges, Angela ;
Faber, Kelley M. ;
Scherer, Martin ;
Fallon, Kenneth B. ;
Riemenschneider, Matthias ;
Fardo, David W. ;
Heun, Reinhard ;
Farlow, Martin R. ;
Koelsch, Heike ;
Ferris, Steven ;
Leber, Markus ;
Foroud, Tatiana M. ;
Heuser, Isabella ;
Galasko, Douglas R. ;
Giegling, Ina ;
Gearing, Marla ;
Huell, Michael ;
Geschwind, Daniel H. ;
Gilbert, John R. ;
Morris, John ;
Green, Robert C. ;
Mayo, Kevin ;
Growdon, John H. ;
Feulner, Thomas ;
Hamilton, Ronald L. ;
Harrell, Lindy E. ;
Drichel, Dmitriy ;
Honig, Lawrence S. ;
Cushion, Thomas D. ;
Huentelman, Matthew J. ;
Hollingworth, Paul ;
Hulette, Christine M. ;
Hyman, Bradley T. ;
Marshall, Rachel ;
Jarvik, Gail P. ;
Meggy, Alun ;
Abner, Erin ;
Menzies, Georgina E. ;
Jin, Lee-Way ;
Leonenko, Ganna ;
Real, Luis M. ;
Jun, Gyungah R. ;
Baldwin, Clinton T. ;
Grozeva, Detelina ;
Karydas, Anna ;
Russo, Giancarlo ;
Kaye, Jeffrey A. ;
Kim, Ronald ;
Jessen, Frank ;
Kowall, Neil W. ;
Vellas, Bruno ;
Kramer, Joel H. ;
Vardy, Emma ;
LaFerla, Frank M. ;
Joeckel, Karl-Heinz ;
Lah, James J. ;
Dichgans, Martin ;
Leverenz, James B. ;
Mann, David ;
Levey, Allan, I ;
Pickering-Brown, Stuart ;
Lieberman, Andrew P. ;
Klopp, Norman ;
Lunetta, Kathryn L. ;
Wichmann, H-Erich ;
Lyketsos, Constantine G. ;
Morgan, Kevin ;
Marson, Daniel C. ;
Brown, Kristelle ;
Martiniuk, Frank ;
Medway, Christopher ;
Mash, Deborah C. ;
Noethen, Markus M. ;
Masliah, Eliezer ;
Hooper, Nigel M. ;
McCormick, Wayne C. ;
Daniele, Antonio ;
McCurry, Susan M. ;
Bayer, Anthony ;
McDavid, Andrew N. ;
Gallacher, John ;
McKee, Ann C. ;
van den Bussche, Hendrik ;
Mesulam, Marsel ;
Brayne, Carol ;
Miller, Bruce L. ;
Riedel-Heller, Steffi ;
Miller, Carol A. ;
Miller, Joshua W. ;
Al-Chalabi, Ammar ;
Morris, John C. ;
Shaw, Christopher E. ;
Myers, Amanda J. ;
Wiltfang, Jens ;
O'Bryant, Sid ;
Olichney, John M. ;
Alvarez, Victoria ;
Parisi, Joseph E. ;
Singleton, Andrew B. ;
Paulson, Henry L. ;
Collinge, John ;
Perry, William R. ;
Mead, Simon ;
Peskind, Elaine ;
Cribbs, David H. ;
Rossor, Martin ;
Pierce, Aimee ;
Ryan, Natalie S. ;
Poon, Wayne W. ;
Nacmias, Benedetta ;
Potter, Huntington ;
Sorbi, Sandro ;
Quinn, Joseph F. ;
Sacchinelli, Eleonora ;
Raj, Ashok ;
Spalletta, Gianfranco ;
Raskind, Murray ;
Caltagirone, Carlo ;
Bossu, Paola ;
Orfei, Maria Donata ;
Reisberg, Barry ;
Clarke, Robert ;
Reitz, Christiane ;
Smith, A. David ;
Ringman, John M. ;
Warden, Donald ;
Roberson, Erik D. ;
Wilcock, Gordon ;
Rogaeva, Ekaterina ;
Bruni, Amalia Cecilia ;
Rosen, Howard J. ;
Gallo, Maura ;
Rosenberg, Roger N. ;
Ben-Shlomo, Yoav ;
Sager, Mark A. ;
Mecocci, Patrizia ;
Saykin, Andrew J. ;
Pastor, Pau ;
Cuccaro, Michael L. ;
Vance, Jeffery M. ;
Schneider, Julie A. ;
Schneider, Lori S. ;
Slifer, Susan ;
Seeley, William W. ;
Smith, Amanda G. ;
Sonnen, Joshua A. ;
Spina, Salvatore ;
Stern, Robert A. ;
Swerdlow, Russell H. ;
Tang, Mitchell ;
Tanzi, Rudolph E. ;
Trojanowski, John Q. ;
Troncoso, Juan C. ;
Van Deerlin, Vivianna M. ;
Van Eldik, Linda J. ;
Vinters, Harry V. ;
Vonsattel, Jean Paul ;
Weintraub, Sandra ;
Welsh-Bohmer, Kathleen A. ;
Wilhelmsen, Kirk C. ;
Williamson, Jennifer ;
Wingo, Thomas S. ;
Woltjer, Randall L. ;
Wright, Clinton B. ;
Yu, Chang-En ;
Yu, Lei ;
Saba, Yasaman ;
Pilotto, Alberto ;
Bullido, Maria J. ;
Peters, Oliver ;
Crane, Paul K. ;
Bennett, David ;
Bosco, Paola ;
Coto, Eliecer ;
Boccardi, Virginia ;
De Jager, Phil L. ;
Lleo, Alberto ;
Warner, Nick ;
Lopez, Oscar L. ;
Ingelsson, Martin ;
Deloukas, Panagiotis ;
Cruchaga, Carlos ;
Graff, Caroline ;
Gwilliam, Rhian ;
Fornage, Myriam ;
Goate, Alison M. ;
Sanchez-Juan, Pascual ;
Kehoe, Patrick G. ;
Amin, Najaf ;
Ertekin-Taner, Nilifur ;
Berr, Claudine ;
Debette, Stphanie ;
Love, Seth ;
Launer, Lenore J. ;
Younkin, Steven G. ;
Dartigues, Jean-Francois ;
Corcoran, Chris ;
Ikram, M. Arfan ;
Dickson, Dennis W. ;
Nicolas, Gael ;
Campion, Dominique ;
Tschanz, JoAnn ;
Schmidt, Helena ;
Hakonarson, Hakon ;
Clarimon, Jordi ;
Munger, Ron ;
Schmidt, Reinhold ;
Farrer, Lindsay A. ;
Van Broeckhoven, Christine ;
O'Donovan, Michael C. ;
DeStefano, Anita L. ;
Jones, Lesley ;
Haines, Jonathan L. ;
Deleuze, Jean-Francois ;
Owen, Michael J. ;
Gudnason, Vilmundur ;
Mayeux, Richard ;
Escott-Price, Valentina ;
Psaty, Bruce M. ;
Ramirez, Alfredo ;
Wang, Li-San ;
Ruiz, Agustin ;
van Duijn, Cornelia M. ;
Holmans, Peter A. ;
Seshadri, Sudha ;
Williams, Julie ;
Amouyel, Phillippe ;
Schellenberg, Gerard D. ;
Lambert, Jean-Charles ;
Pericak-Vance, Margaret A.
作者单位：
Univ Eastern Finland, Inst Biomed, Kuopio, Finland
[1]
Univ Washington, Dept Neurol, Seattle, WA 98195 USA
[2]
Univ Calif Davis, Dept Neurol, Sacramento, CA 95817 USA
[3]
Univ Miami, Dept Neurol, Miami, FL USA
[4]
Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10467 USA
[5]
Univ Penn, Perelman Sch Med, Dept Pathol & Lab Med, Philadelphia, PA 19104 USA
[6]
Univ Hosp, Dept Psychiat & Psychotherapy, Saarland, Germany
[7]
Univ Alabama Birmingham, Dept Neurol, UAB Stn, Birmingham, AL 35294 USA
[8]
Univ Washington, Natl Alzheimers Coordinating Ctr, Seattle, WA 98195 USA
[9]
La Colombiere Hosp, Inserm Neuropsychiat U1061, Montpellier, France
[10]
Univ Florence, Dept Neurosci Psychol Drug Res & Child Hlth, Florence, Italy
[11]
Columbia Univ, Med Ctr, Dept Neurol, Ctr Translat & Computat Neuroimmunol, New York, NY USA
[12]
Univ Kentucky, Sanders Brown Ctr Aging, Dept Biostat, Lexington, KY 40536 USA
[13]
Univ Texas Hlth Sci Ctr Houston, Human Genet Ctr, Sch Publ Hlth, Houston, TX 77030 USA
[14]
Univ Calif Irvine, Dept Neurobiol & Behav, Irvine, CA USA
[15]
Univ Parma, DIMEC, Sect Neurosci, Parma, Italy
[16]
Hop La Pitie Salpetriere, Dept Neurol, Inst Memoire & Malad Alzheimer, Paris, France
[17]
Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA
[18]
Univ Texas Southwestern Med Ctr Dallas, Dept Psychiat, Dallas, TX 75390 USA
[19]
Karolinska Inst, Dept Neurobiol Care Sci & Soc, Aging Res Ctr, Stockholm, Sweden
[20]
Framingham Heart Dis Epidemiol Study, Framingham, MA USA
[21]
Dublin City Univ, Sch Biotechnol, Dublin, Ireland
[22]
Kaiser Permanente, Washington Hlth Res Inst, Seattle, WA USA
[23]
Catholic Univ Sacred Hearth, Inst Neurol, Rome, Italy
[24]
Mayo Clin, Dept Neurol, Rochester, MN USA
[25]
Univ Paris Saclay, CEA, Inst Biol Francois Jacob, Ctr Natl Rech Genom Humaine, Evry, France
[26]
Newcastle Univ, Inst Ageing & Hlth, Newcastle Upon Tyne, Tyne & Wear, England
[27]
Univ Antwerp, Inst Born Bunge, Lab Neurochem & Behav, Antwerp, Belgium
[28]
Duke Univ, Dept Neurol, Durham, NC USA
[29]
UCL Inst Neurol, UK Dementia Res Inst UCL, Dept Neurodegenerat Dis, London, England
[30]
Kings Coll London, Inst Psychiat Psychol & Neurosci, London, England
[31]
Univ Erlangen Nurnberg, Dept Psychiat & Psychotherapy, Erlangen, Germany
[32]
Med Univ Lodz, Elderly & Psychiat Disorders Dept, Lodz, Poland
[33]
Klinikum Univ Munchen, Inst Stroke & Dementia Res, Munich, Germany
[34]
Univ Calif San Francisco, Memory & Aging Ctr, Weill Inst Neurosci, San Francisco, CA 94143 USA
[35]
Univ Southern Calif, Dept Pathol, Los Angeles, CA USA
[36]
Utah State Univ, Logan, UT 84322 USA
[37]
Univ Bonn, Dept Psychiat & Psychotherapy, Bonn, Germany
[38]
Somerset Partnership NHS Trust, Somerset, England
[39]
Univ Calif Irvine, Inst Memory Impairments & Neurol Disorders, Irvine, CA USA
[40]
Univ Texas Southwestern Med Ctr Dallas, Dept Neurol, Dallas, TX 75390 USA
[41]
UCL Inst Neurol, Dept Neurodegenerat Dis, London, England
[42]
Univ Med Ctr Goettingen, Dept Psychiat & Psychotherapy, Gottingen, Germany
[43]
Univ Cagliari, Dept Biomed Sci, Sect Neurosci & Clin Pharmacol, Cagliari, Italy
[44]
Univ Penn, Perelman Sch Med, Dept Pathol & Lab Med, Penn Neurodegenerat Genom Ctr, Philadelphia, PA
[45]
Univ Eastern Finland, AI Virtanen Inst Mol Sci, Kuopio, Finland
[46]
Univ Southern Calif, Keck Sch Med, Dept Neurol, Los Angeles, CA USA
[47]
Inserm, RID AGE Risk Factors & Mol Determinants Aging Rel, U1167, Lille, France
[48]
Martin Luther Univ Halle Wittenberg, Dept Psychiat, Halle, Germany
[49]
Univ Cent Asturias, Mol Genet Lab Hosp, Oviedo, Spain
[50]
UCL, Div Psychiat, London, England
[51]
Heidelberg Univ, Med Fac Mannheim, Cent Inst Mental Hlth, Heidelberg, Germany
[52]
Univ Calif Los Angeles, Dept Neurol, Los Angeles, CA 90024 USA
[53]
NIA, Lab Epidemiol & Populat Sci, Bethesda, MD 20892 USA
[54]
Univ Perugia, Dept Med, Sect Gerontol & Geriatr, Perugia, Italy
[55]
Univ Cologne, Dept Psychiat & Psychotherapy, Cologne, Germany
[56]
Banner Sun Hlth Res Inst, Civin Lab Neuropathol, Phoenix, AZ USA
[57]
Univ Calif San Diego, Dept Neurosci, La Jolla, CA 92093 USA
[58]
Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Basic & Clin Neurosci, London, England
[59]
Indiana Univ, Dept Med & Mol Genet, Indianapolis, IN 46204 USA
[60]
Charite, Dept Psychiat & Psychotherapy, Berlin, Germany
[61]
Iceland Heart Assoc, Kopavogur, Iceland
[62]
Univ Freiburg, Dept Psychiat, Freiburg, Germany
[63]
Harvard Univ, Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA
[64]
Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA
[65]
CMRR Bordeaux, Memory Res & Resources Ctr, Bordeaux, France
[66]
Texas Tech Univ, Hlth Sci Ctr, Dept Neurol, Lubbock, TX 79409 USA
[67]
Case Western Reserve Univ, Dept Populat & Quantitat Hlth Sci, Inst Computat Biol, Cleveland, OH
[68]
Brd Inst, Program Med & Populat Genet, Cambridge, MA USA
[69]
Univ Oxford, Clin Trial Serv Unit, Oxford Hlth Aging Project, Oxford, England
[70]
Harvard Med Sch, Massachusetts Gen Hosp, Dept Neurol, Boston, MA 02115 USA
[71]
Univ Penn, Dept Psychiat, Perelman Sch Med, Philadelphia, PA 19104 USA
[72]
Univ Washington, Dept Family Med, Seattle, WA 98195 USA
[73]
Univ Calif Irvine, Dept Pathol & Lab Med, Irvine, CA USA
[74]
Inst Prion Dis, MRC Prion Unit UCL, Dept Neurodegenerat Dis, London, England
[75]
Univ Penn, Perelman Sch Med, Childrens Hosp Philadelphia, Ctr Appl Genom, Philadelphia, PA 19104 USA
[76]
Johns Hopkins Univ, Dept Psychiat, Baltimore, MD USA
[77]
Univ Calif Davis, Dept Pathol & Lab Med, Sacramento, CA 95817 USA
[78]
IRCCS Santa Lucia Fdn, Lab Neuropsychiat, Rome, Italy
[79]
Univ Pittsburgh, Dept Psychiat, Pittsburgh, PA USA
[80]
Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands
[81]
Univ Bristol, Learning & Res Level 2, Med Sch, Southmead Hosp, Bristol, Avon, England
[82]
Massachusetts Gen Hosp, CS Kub Lab Neuropathol, Charlestown, MA USA
[83]
Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Old Age Psychiat, London, England
[84]
Univ Med Ctr Hamburg Eppendorf, Dept Primary Med Care, Hamburg, Germany
[85]
Wellcome Trust Sanger Inst, Cambridge, England
[86]
Univ Calif Los Angeles, Neurogenet Program, Los Angeles, CA USA
[87]
Univ Texas Southwestern Med Ctr Dallas, Dept Surg, Dallas, TX 75390 USA
[88]
Northwestern Univ, Feinberg Sch Med, Dept Pathol, Chicago, IL 60611 USA
[89]
Univ Miami, Miller Sch Med, John P Hussman Inst Human Genom, Miami, FL 33136 USA
[90]
Harbor UCLA Med Ctr, Los Angeles BioMed Res Inst, Dept Pediat, Inst Translat Genom & Populat Sci
[91]
Translat Genom Res Inst, Neurogen Div, Phoenix, AZ USA
[92]
German Ctr Neurodegenerat Dis, Bonn, Germany
[93]
Univ Calif San Francisco, Dept Neuropsychol, San Francisco, CA 94143 USA
[94]
Duke Univ, Dept Pathol, Durham, NC 27706 USA
[95]
Univ Bari, Ctr Aging Brain, Dept Geriatr, Bari, Italy
[96]
Boston Univ, Sch Med, Dept Med, Sect Computat Biomed, Boston, MA 02118 USA
[97]
Univ S Florida, USF Hlth Byrd Alzheimers Inst, Tampa, FL USA
[98]
Helmholtz Ctr Munich, Inst Epidemiol, Munich, Germany
[99]
Univ Calif San Francisco, Dept Neurol, San Francisco, CA USA
[100]
Fdn IRCCS Ca Granda, Osped Maggiore Policlin, Neurodegenerat Dis Unit, Milan, Italy
[101]
Washington Univ, Sch Med, Dept Psychiat, St Louis, MO 63110 USA
[102]
Univ Kansas, Med Ctr, Alzheimers Dis Ctr, Kansas City, KS 66103 USA
[103]
Hosp Univ Doctor Negrin, Dept Immunol, Las Palmas Gran Canaria, Spain
[104]
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发布时间
2019-10-15
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Nature Genetics
Nature Genetics
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