Activation of Nrf2/AREs-mediated antioxidant signalling, and suppression of profibrotic TGF-beta 1/Smad3 pathway: a promising therapeutic strategy for hepatic fibrosis

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Activation of Nrf2/AREs-mediated antioxidant signalling, and suppression of profibrotic TGF-beta 1/Smad3 pathway: a promising therapeutic strategy for hepatic fibrosis - A review

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第一作者： Gong, Yongfang

作者： Gong, Yongfang ^[1] ; Yang, Yan

作者单位： Anhui Med Univ, Dept Pharmacol, Key Lab Antiinflammatory & Immunopharmacol, Minist Educ, 81 Meishan ^[1]

关键词 Liver fibrosis Activated hepatic stellate cell Nuclear erythroid 2-related factor 2 Transforming growth factor-beta/Smad Oxidative stress COOH-terminally-phosphorylated R-Smad (pSmad2C and pSmad3C)Linker region phosphorylated R-Smad (pSmad2L and pSmad3L)

发布时间 2022-05-08

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Activation of Nrf2/AREs-mediated antioxidant signalling, and suppression of profibrotic TGF-beta 1/Smad3 pathway: a promising therapeutic strategy for hepatic fibrosis - A review

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Activation of Nrf2/AREs-mediated antioxidant signalling, and suppression of profibrotic TGF-beta 1/Smad3 pathway: a promising therapeutic strategy for hepatic fibrosis - A review

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