Effects of Membrane PEGylation on Entry and Location of Antifungal Drug Itraconazole and Their Pharmacological Implications

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作者： Dzieciuch-Rojek, Monika ^[1] ; Poojari, Chetan ^[2] ; Bednar, Jan ^[3] ; Bunker, Alex ^[4] ; Kozik, Bartlomiej ; Nowakowska, Maria ; Vattulainen, Ilpo ; Wydro, Pawel ; Kepczynski, Mariusz ; Rog, Tomasz

作者单位： Tampere Univ Technol, Dept Phys, POB 692, FI-33101 Tampere, Finland ^[1] Univ Helsinki, Div Pharmaceut Biosci, Ctr Drug Res, Fac Pharm, FI-00014 Helsinki, Finland ^[2] Jagiellonian Univ, Fac Chem, Ingardena 3, PL-30060 Krakow, Poland ^[3] Univ Grenoble Alpes, CNRS, Inst Albert Bonniot, UMR 5309, F-38042 Grenoble 9, France ^[4]

关键词 lipid bilayer itraconazole sterically stabilized liposomes ciyo-TEM polyethylene glycol (PEG)molecular dynamics simulations

发布时间 2018-04-25

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