Differentiation of rare brain tumors through unsupervised machine learning: Clinical significance of in-depth methylation and copy number profiling illustrated through an unusual case of IDH wildtype glioblastoma

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作者： Saleh, Christian ^[1] ; Jaszczuk, Phillip ^[2] ; Hund-Georgiadis, Margret ^[3] ; Frank, Stephan ^[4] ; Cordier, Dominik ^[5] ; Hench, Ivana Bratic ^[6] ; Todea, Alexandra ; Wasilewski, Andrea ; Wilmes, Stefanie ; Grigioni, Giulia ; Hench, Juergen

作者单位： Univ Hosp Basel, Dept Neurosurg, Basel, Switzerland ^[1] Univ Basel, Univ Hosp Basel, Div Neuropathol, Inst Med Genet & Pathol, Basel, Switzerland ^[2] Univ Hosp Basel, Dept Neurophysiol & Neurol, Basel, Switzerland ^[3] Univ Rochester, Med Ctr, Dept Neurol, Div Neurooncol, Rochester, NY 14642 USA ^[4] Univ Hosp Basel, Clin Radiol & Nucl Med, Dept Neuroradiol, Basel, Switzerland ^[5] REHAB Basel, Ctr Neurorehabil & Paraplegiol, Basel, Switzerland ^[6]

关键词 brain tumor molecular diagnostics methylation profiling glioma mutation unsupervised machine learning

发布时间 2021-07-24

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