Design, synthesis, and activity of a series of pyrrolidine-3-carboxylic acid-based, highly specific, orally active ET(B) antagonists containing a diphenylmethylamine acetamide side chain.

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作者： Liu G ^[1] ; Kozmina NS ; Winn M ; von Geldern-TW ; Chiou WJ ; Dixon DB ; Nguyen B ; Marsh KC ; Opgenorth TJ

作者单位： Metabolic Disease Research and Drug Analysis Department, Pharmaceutical Products Division, Abbott Laboratories, Abbott Park, Illinois 60064-6098, USA. gang.liu@abbott.com ^[1]

关键词 Acetamides Methylamines Proline Pyrrolidines Receptors Endothelin endothelin A receptor 乙酰胺类甲胺类脯氨酸吡咯烷类受体内皮缩血管肽

发布时间 2013-11-20

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Journal of Medicinal Chemistry

1999年42卷18期

3679-3689页

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Design, synthesis, and activity of a series of pyrrolidine-3-carboxylic acid-based, highly specific, orally active ET(B) antagonists containing a diphenylmethylamine acetamide side chain.

Journal of Medicinal Chemistry

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Journal of Medicinal Chemistry

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Design, synthesis, and activity of a series of pyrrolidine-3-carboxylic acid-based, highly specific, orally active ET(B) antagonists containing a diphenylmethylamine acetamide side chain.

Journal of Medicinal Chemistry

相似文献

Journal of Medicinal Chemistry

相关期刊

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