Transcriptional Regulation of X-Box-binding Protein One (XBP1) by Hepatocyte Nuclear Factor 4 (HNF4) Is Vital to Beta-cell Function

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作者： Moore, Benjamin D. ^[1] ; Jin, Ramon U. ^[2] ; Lo, Heiyong ^[3] ; Jung, Min ^[4] ; Wang, Haiyan ^[5] ; Battle, Michele A. ; Wollheim, Claes B. ; Urano, Fumihiko ; Mills, Jason C.

作者单位： F Hoffmann La Roche Ltd, Roche Innovat Ctr Basel, Roche Pharma Res & Early Dev, Grenzacherstr 124 ^[1] Med Coll Wisconsin, Dept Cell Biol Neurobiol & Anat, Milwaukee, WI 53226 USA ^[2] Washington Univ, Sch Med, Div Endocrinol, Dept Med, St Louis, MO 63110 USA ^[3] Washington Univ, Div Gastroenterol, Dept Med, St Louis, MO 63110 USA ^[4] Lund Univ, Skane Univ Hosp, Ctr Diabet, Dept Clin Sci Diabet & Endocrinol, S-20502 Malmo, Sweden ^[5]

关键词 beta cell (B-cell)endoplasmic reticulum (ER)hepatocyte nuclear factor 4 (HNF-4)insulin secretion X-box binding protein 1 (XBP1)

发布时间 2017-05-26

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