换一批
换一批A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm
作者：
Ridder, Bradley J. [1]
;
Leishman, Derek J. [2]
;
Bridgland-Taylor, Matthew [3]
;
Samieegohar, Mohammadreza [4]
;
Han, Xiaomei [5]
;
Wu, Wendy W. [6]
;
Randolph, Aaron [7]
;
Phu Tran [8]
;
Sheng, Jiansong [9]
;
Danker, Timm [10]
;
Lindqvist, Anders [11]
;
Konrad, Daniel [12]
;
Hebeisen, Simon [13]
;
Polonchuk, Liudmila [14]
;
Gissinger, Evgenia [15]
;
Renganathan, Muthukrishnan [16]
;
Koci, Bryan [17]
;
Wei, Haiyang [18]
;
Fan, Jingsong ;
Levesque, Paul ;
Kwagh, Jae ;
Imredy, John ;
Zhai, Jin ;
Rogers, Marc ;
Humphries, Edward ;
Kirby, Robert ;
Stoelzle-Feix, Sonja ;
Brinkwirth, Nina ;
Rotordam, Maria Giustina ;
Becker, Nadine ;
Friis, Soren ;
Rapedius, Markus ;
Goetze, Tom A. ;
Strassmaier, Tim ;
Okeyo, George ;
Kramer, James ;
Kuryshev, Yuri ;
Wu, Caiyun ;
Himmel, Herbert ;
Mirams, Gary R. ;
Strauss, David G. ;
Bardenet, Remi ;
Li, Zhihua
作者单位：
Univ Nottingham, Ctr Math Med & Biol, Sch Math Sci, Nottingham, England
[1]
Merck & Co Inc, Kenilworth, NJ USA
[2]
Univ Lille, Cent Lille, CNRS, UMR 9189,CRIStAL, Villeneuve Dascq, France
[3]
Sophion Biosci AS, Baltorpvej 154, DK-154 Ballerup, Denmark
[4]
Bristol Myers Squibb Co, Bristol Myers Squibb, Discovery Toxicol, 3551 Lawrenceville,Princeton Rd
[5]
US FDA, Div Appl Regulatory Sci, Off Clin Pharmacol, Off Translat Sci,Ctr Drug Evaluat & Res, 10903
[6]
Nanion Technol USA, 1 Naylon Pl,Suite C, Livingston, NJ 07039 USA
[7]
BSYS GmbH, Benkenstr 254, CH-4108 Witterswil, Switzerland
[8]
AstraZeneca, R&D, Clin Pharmacol & Safety Sci, Cambridge, England
[9]
Bayer AG, RD TS TOX SP-SPL1,Aprather Weg 18a, D-42096 Wuppertal, Germany
[10]
CiPA Lab, 900 Clopper Rd,Suite 130, Gaithersburg, MD 20878 USA
[11]
Charles River Labs, 14656 Neo Pkwy, Cleveland, OH 44128 USA
[12]
F Hoffmann La Roche & Cie AG, F Hoffmann La Roche Ltd Bldg 73-R, CH-4070 Basel, Switzerland
[13]
Eli Lilly & Co, Dept Toxicol & Pathol, Indianapolis, IN 46285 USA
[14]
NMI TT GmbH, Markwiesenstr 55, D-72770 Reutlingen, Germany
[15]
Nanion Technol Munich, Ganghoferstr 70A, D-80339 Munich, Germany
[16]
Eurofins Discovery, Eurofins Sci, 6 Res Pk Dr, St Charles, MO 63304 USA
[17]
Metrion Biosci Ltd, Riverside 3,Suite 1,Granta Pk, Cambridge CB21 6AD, England
[18]
发布时间
2020-10-12
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