First-in-human study of CPL207280, a novel G-protein-coupled receptor 40/free fatty acid receptor 1 agonist, in healthy volunteers after single and multiple administration

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作者： Bazydlo-Guzenda, Katarzyna ^[1] ; Jarus-Dziedzic, Katarzyna ^[2] ; Gierczak-Pachulska, Agnieszka ^[3] ; Buda, Pawel ^[4] ; Rudzki, Piotr J. ^[5] ; Bus-Kwasnik, Katarzyna ^[6] ; Juszczyk, Ewelina ^[7] ; Tratkiewicz, Ewa ; Rabczenko, Daniel ; Segiet-Swiecicka, Agnieszka ; Wieczorek, Maciej

作者单位： Biores Grp ^[1] Biores GrpCelon Pharm SA R&D Ctr ^[2] Biores GrpCelon Pharm SA R&D Ctr Celon Pharm SA R&D Ctr ^[3] Biores GrpCelon Pharm SA R&D Ctr Celon Pharm SA R&D Ctr Celon Pharm SA R&D Ctr ^[4] Biores GrpCelon Pharm SA R&D Ctr Celon Pharm SA R&D Ctr Celon Pharm SA R&D Ctr Lukasiewicz Res ^[5] Cleandatalabs ^[6] CleandatalabsCelon Pharm SA R&D Ctr ^[7]

关键词 drug development pharmacodynamics pharmacokinetics phase I-II study type 2 diabetes GPR40/FFAR1 FASIGLIFAM TAK-875 GLYCEMIC CONTROL GPR40 AGONIST DOUBLE-BLIND PHASE-III SAFETY PHARMACOKINETICS

发布时间 2024-05-18

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准确一般字义偏差语意偏离译文作用小提交