Characterisation of Ppy-lineage cells clarifies the functional heterogeneity of pancreatic beta cells in mice

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作者： Fukaishi, Takahiro ^[1] ; Nakagawa, Yuko ^[2] ; Fukunaka, Ayako ^[3] ; Sato, Takashi ^[4] ; Hara, Akemi ^[5] ; Nakao, Keiko ^[6] ; Saito, Michiko ^[7] ; Kohno, Kenji ; Miyatsuka, Takeshi ; Tamaki, Motoyuki ; Matsuhisa, Munehide ; Matsuoka, Taka-aki ; Yamada, Tetsuya ; Watada, Hirotaka ; Fujitani, Yoshio

作者单位： Gunma Univ, Lab Dev Biol & Metab, Inst Mol & Cellular Regulat, Gunma, Japan ^[1] Tokushima Univ, Diabet Therapeut & Res Ctr, Inst Adv Med Sci, Tokushima, Japan ^[2] Juntendo Univ, Dept Metab & Endocrinol, Grad Sch Med, Tokyo, Japan ^[3] Tokyo Med & Dent Univ, Grad Sch Med & Dent Sci, Dept Mol Endocrinol & Metab, Tokyo, Japan ^[4] Nara Inst Sci & Technol NAIST, Inst Res Initiat, Nara, Japan ^[5] Saitama Med Univ, Fac Med, Dept Physiol, Saitama, Japan ^[6] Wakayama Med Univ, Dept Med 1, Wakayama, Japan ^[7]

关键词 Beta cell heterogeneity Ca2+ imaging Diphtheria toxin GLUT2 Pancreatic polypeptide Ppy Single-cell RNA sequence Streptozotocin TSPAN8 UCN3

发布时间 2021-12-18

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