Physicochemical effect of the N501Y, E484K/Q, K417N/T, L452R and T478K mutations on the SARS-CoV-2 spike protein RBD and its influence on agent fitness and on attributes developed by emerging variants of concern-论文-万方医学网

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Physicochemical effect of the N501Y, E484K/Q, K417N/T, L452R and T478K mutations on the SARS-CoV-2 spike protein RBD and its influence on agent fitness and on attributes developed by emerging variants of concern

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第一作者： Ponde, R. A. A.

作者： Ponde, R. A. A. ^[1]

作者单位： Superintendence Hlth Surveillance SUVISA GO,State Dept Hlth SES ^[1]

关键词 SARS-CoV-2 Mutation Receptor binding domain Physicochemical effects Variant of concern RECEPTOR-BINDING DOMAIN VIRAL INFECTIVITY B.1.1.7 P.1 NEUTRALIZATION B.1.617.2

发布时间 2022-11-20

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Physicochemical effect of the N501Y, E484K/Q, K417N/T, L452R and T478K mutations on the SARS-CoV-2 spike protein RBD and its influence on agent fitness and on attributes developed by emerging variants of concern

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Physicochemical effect of the N501Y, E484K/Q, K417N/T, L452R and T478K mutations on the SARS-CoV-2 spike protein RBD and its influence on agent fitness and on attributes developed by emerging variants of concern

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