换一批Genetic invalidation of Lp-PLA(2) as a therapeutic target: Large-scale study of five functional Lp-PLA(2)-lowering alleles
作者：
Gregson, John M. [1]
;
Freitag, Daniel F. [2]
;
Surendran, Praveen [3]
;
Stitziel, Nathan O. [4]
;
Chowdhury, Rajiv [5]
;
Burgess, Stephen [6]
;
Kaptoge, Stephen [7]
;
Gao, Pei [8]
;
Staley, James R. [9]
;
Willeit, Peter [10]
;
Nielsen, Sune F. [11]
;
Caslake, Muriel [12]
;
Trompet, Stella [13]
;
Polfus, Linda M. [14]
;
Kuulasmaa, Kari [15]
;
Kontto, Jukka [16]
;
Perola, Markus [17]
;
Blankenberg, Stefan [18]
;
Veronesi, Giovanni [19]
;
Gianfagna, Francesco [20]
;
Mannisto, Satu [21]
;
Kimura, Akinori [22]
;
Lin, Honghuang [23]
;
Reilly, Dermot F. [24]
;
Gorski, Mathias [25]
;
Mijatovic, Vladan [26]
;
Munroe, Patricia B. [27]
;
Ehret, Georg B. [28]
;
Thompson, Alex [29]
;
Uria-Nickelsen, Maria [30]
;
Malarstig, Anders [31]
;
Dehghan, Abbas [32]
;
Vogt, Thomas F. [33]
;
Sasaoka, Taishi [34]
;
Takeuchi, Fumihiko [35]
;
Kato, Norihiro [36]
;
Yamada, Yoshiji [37]
;
Kee, Frank [38]
;
Mueller-Nurasyid, Martina ;
Ferrieres, Jean ;
Arveiler, Dominique ;
Amouyel, Philippe ;
Salomaa, Veikko ;
Boerwinkle, Eric ;
Thompson, Simon G. ;
Ford, Ian ;
Jukema, J. Wouter ;
Sattar, Naveed ;
Packard, Chris J. ;
Majumder, Abdulla al Shafi ;
Alam, Dewan S. ;
Deloukas, Panos ;
Schunkert, Heribert ;
Samani, Nilesh J. ;
Kathiresan, Sekar ;
Nordestgaard, Borge G. ;
Saleheen, Danish ;
Howson, Joanna M. M. ;
Di Angelantonio, Emanuele ;
Butterworth, Adam S. ;
Danesh, John
作者单位：
Cambridge & Massachusetts Gen Hosp, Broad Inst, Boston, MA USA
[1]
Univ Glasgow, Glasgow G12 8QQ, Lanark, Scotland
[2]
St Michael Hosp, Ctr Global Hlth Res, Toronto, ON, Canada
[3]
Helmholtz Zentrum Munchen German Res Ctr Environm, Inst Genet Epidemiol, Neuherberg, Germany
[4]
Univ Penn, Philadelphia, PA 19104 USA
[5]
Merck Res Labs, Genet & Pharmacogen, Boston, MA USA
[6]
Partner Site Munich Heart Alliance, DZHK German Ctr Cardiovasc Res, Munich, Germany
[7]
Univ Verona, Dept Life & Reprod Sci, I-37100 Verona, Italy
[8]
Inst Pasteur, Dept Epidemiol & Publ Hlth, Lille, France
[9]
THL Natl Inst Hlth & Welf, Helsinki, Finland
[10]
Natl Ctr Global Hlth & Med, Res Inst, Dept Gene Diagnost & Therapeut, Tokyo, Japan
[11]
Queen Mary Univ London, Barts & London Sch Med & Dent, William Harvey Res Inst, London, England
[12]
Queen Mary Univ London, Clin Pharmacol & Genome Ctr, William Harvey Res Inst, Barts & London Sch
[13]
Washington Univ, Sch Med, Dept Med, St Louis, MO 63110 USA
[14]
Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge CB2 1TN
[15]
Queens Univ, UKCRC Ctr Excellence Publ Hlth, Belfast, Antrim, Ireland
[16]
Univ Copenhagen, Copenhagen Univ Hosp, DK-1168 Copenhagen, Denmark
[17]
Merck Res Labs, Cardiometabol Dis, Kenilworth, NJ USA
[18]
Univ Helsinki, Inst Mol Med FIMM, FIN-00014 Helsinki, Finland
[19]
Univ Heart Ctr Hamburg, Dept Gen & Intervent Cardiol, Hamburg, Germany
[20]
Pfizer Worldwide R&D, Clin Res, Sollentuna, Sweden
[21]
Natl Inst Cardiovasc Dis, Dhaka, Bangladesh
[22]
Univ Texas Hlth Sci Ctr Houston, Ctr Human Genet, Houston, TX USA
[23]
Erasmus Univ, Med Ctr, Dept Epidemiol, Rotterdam, Netherlands
[24]
Leiden Univ, Med Ctr, NL-2300 RA Leiden, Netherlands
[25]
UCB, Brussels, Belgium
[26]
Mie Univ, Life Sci Res Ctr, Dept Human Funct Genom, Tsu, Mie, Japan
[27]
Toulouse Univ, CHU Toulouse, Dept Epidemiol, INSERM,UMR 1027, Toulouse, France
[28]
Boston Univ, Sch Med, Dept Med, Sect Computat Biomed, Boston, MA 02215 USA
[29]
Univ Strasbourg, Dept Epidemiol & Publ Hlth, EA 3430, Strasbourg, France
[30]
Tokyo Med & Dent Univ, Med Res Inst, Dept Mol Pathogenesis, Tokyo, Japan
[31]
Univ Regensburg, Dept Genet Epidemiol, D-93053 Regensburg, Germany
[32]
Univ Insubria, Dept Clin & Expt Med, Res Ctr, Varese, Italy
[33]
Univ Cambridge, Dept Publ Hlth & Primary Care, Cambridge CB2 1TN, England
[34]
Johns Hopkins Univ, Sch Med, Ctr Complex Dis Genom, McKusick Nathans Inst Genet Med, Baltimore, MD
[35]
Pfizer Worldwide R&D, Clin Res, Cambridge, MA USA
[36]
Univ Texas Hlth Sci Ctr Houston, Houston, TX 77030 USA
[37]
Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England
[38]
发布时间
2017-10-25
- 浏览1
European journal of preventive cardiology
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