Calcific Aortic Valve Disease: Part 2-Morphomechanical Abnormalities, Gene Reexpression, and Gender Effects on Ventricular Hypertrophy and Its Reversibility
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关键词
Blood flowAortic valvular stenosisPressure overloadTransvalvular gradientPhysiological cardiac hypertrophyPathological cardiac hypertrophy and failureReceptor tyrosine kinasesPI3K(p110 alpha)lipid kinase-Akt serine/threonine kinase pathwayG protein-coupled receptorsMitogen-activated protein kinasesExtracellular signal-regulated kinases 1 and 2CalcineurinReplication of cardiomyocyte sarcomeres in-parallel and in-seriesConcentric LV hypertrophySubendocardial ischemiaFetal gene reexpressionCardiomyocyte apoptosisMyocardial fibrosisMitochondrial biogenesisMyocardial hypertrophic and hyperplastic growthResident endogenous stem/progenitor cells and myocardial regeneration
发布时间
2017-04-15
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