Bis(het)aryl-1,2,3-triazole quinuclidines as alpha 7 nicotinic acetylcholine receptor ligands: Synthesis, structure affinity relationships, agonism activity, [F-18]-radiolabeling and PET study in rats

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作者： Ouach, Aziz ^[1] ; Vercouillie, Johnny ^[2] ; Bertrand, Emilie ^[3] ; Rodrigues, Nuno ^[4] ; Pin, Frederic ; Serriere, Sophie ; Boiaryna, Liliana ; Chartier, Agnes ; Percina, Nathalie ; Tangpong, Pakorn ; Gulhan, Zuhal ; Mothes, Celine ; Deloye, Jean-Bernard ; Guilloteau, Denis ; Page, Guylene ; Suzenet, Franck ; Buron, Frederic ; Chalon, Sylvie ; Routier, Sylvain

作者单位： Zionexa, 42 Ave Grande Armee, F-75017 Paris, France ^[1] Univ Orleans, Inst Chim Organ & Analyt, CNRS, UMR 7311, Rue Chartres,BP 6759, F-45067 Orleans 2 ^[2] Univ Tours, INSERM, UMR 1253, Brain, Tours, France ^[3] Univ Poitiers, NEUVACOD, EA3808, 1 Rue Georges Bonnet,TSA 51106, F-86073 Poitiers 9, France ^[4]

关键词 Triazole Quinuclidine SAR Agonism Radiolabeling F-18 PET Alpha 7 nicotinic acetylcholine receptor

发布时间 2020-02-26

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European Journal of Medicinal Chemistry

2019年179卷

449-469页

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Bis(het)aryl-1,2,3-triazole quinuclidines as alpha 7 nicotinic acetylcholine receptor ligands: Synthesis, structure affinity relationships, agonism activity, [F-18]-radiolabeling and PET study in rats

European Journal of Medicinal Chemistry

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European Journal of Medicinal Chemistry

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Bis(het)aryl-1,2,3-triazole quinuclidines as alpha 7 nicotinic acetylcholine receptor ligands: Synthesis, structure affinity relationships, agonism activity, [F-18]-radiolabeling and PET study in rats

European Journal of Medicinal Chemistry

相似文献

European Journal of Medicinal Chemistry

相关期刊

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