AMPK downregulates ALK2 via increasing the interaction between Smurf1 and Smad6, leading to inhibition of osteogenic differentiation

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作者： Hui Lin ^[1] ; Ying Ying ^[2] ; Yuan-Yuan Wang ^[3] ; Gang Wang ^[4] ; Shan-Shan Jiang ^[5] ; Deqinag Huang ^[6] ; Lingyu Luo ; Ye-Guang Chen ; Louis C. Gerstenfeld ; Zhijun Luo

作者单位： Department of Orthopaedic Surgery, Boston University School of Medicine ^[1] Jiangxi Province Key Laboratory of Tumor Pathogenesis and Molecular Pathology, Department of ^[2] The Institute of Digestive Diseases, The First Affiliated Hospital, Nanchang University ^[3] Department of Cardiology, Boston Children's Hospital ^[4] Department of Biochemistry, Boston University School of Medicine ^[5] School of Life Sciences, Tsinghua University ^[6]

关键词 Fibrodysplasia ossificans progressiva Activin A receptor type I/activin receptor like kinase 2 AMP-activated protein kinase Osteogenic differentiation iPS

发布时间 2018-04-18

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