Skin Treatment with Detergent Induces Dermatitis with H1-Antihistamine-Refractory Itch and Upregulates IL-4 and Th17/Th22 Cytokine Gene Expression in C57BL/6 Mice

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作者： Yurie,Masutani ^[1] ; Toshiro,Takai ^[2] ; Seiji,Kamijo ^[3] ; Toru,Kimitsu ^[4] ; Tomoko,Yoshimura ; Saori,Ichikawa ; Saya,Shimizu ; Takasuke,Ogawa ; Keiko,Takada ; Mitsutoshi,Tominaga ; Hajime,Suto ; Kenji,Takamori ; Hideoki,Ogawa ; Ko,Okumura ; Shigaku,Ikeda

作者单位： Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan ^[1] Department of Chemical and Biological Sciences, Faculty of Science, Japan Women’s University, Tokyo ^[2] Department of Dermatology and Allergology, Juntendo University Graduate School of Medicine, Tokyo ^[3] Juntendo Itch Research Center (JIRC), Institute for Environmental and Gender-Specific Medicine ^[4]

关键词 Murine model Detergent-induced irritant contact dermatitis H1-antihistamine-refractory dermatitis IL-4 Th17/Th22 cytokines

发布时间 2023-02-04

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