首页> Journal of Medicinal Chemistry> Design and Synthesis of a Series of L-trans-4-Substituted Prolines as Selective Antagonists for the lonotropic Glutamate Receptors Including Functional and X-ray Crystallographic Studies of New Subtype Selective Kainic Acid Receptor Subtype 1 (GIuK1) Antagonist (2S,4R)-4-(2-Carboxyphenoxy)pyrrolidine-2-carboxylic Acid

Design and Synthesis of a Series of L-trans-4-Substituted Prolines as Selective Antagonists for the lonotropic Glutamate Receptors Including Functional and X-ray Crystallographic Studies of New Subtype Selective Kainic Acid Receptor Subtype 1 (GIuK1) Antagonist (2S,4R)-4-(2-Carboxyphenoxy)pyrrolidine-2-carboxylic Acid

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第一作者： Krogsgaard-Larsen, Niels

作者： Krogsgaard-Larsen, Niels ^[1] ; Delgar, Claudia G. ^[2] ; Koch, Karina ^[3] ; Brown, Patricia M. G. E. ^[4] ; Moller, Charlotte ^[4] ; Han, Liwei ^[1] ; Huynh, Tri H. V. ^[1] ; Hansen, Stinne W. ^[1] ; Nielsen, Birgitte ^[1] ; Bowie, Derek ^[1] ; Pickering, Darryl S. ^[5] ; Kastrup, Jette Sandholm ^[2] ; Frydenvang, Karla ^[2] ; Bunch, Lennart ^[5]

作者单位： Univ Copenhagen, Fac Hlth & Med Sci, Bunch Res Grp, Univ Pk 2, DK-2100 Copenhagen, Denmark ^[1] Univ Copenhagen, Fac Hlth & Med Sci, Biostruct Res Grp, Univ Pk 2, DK-2100 Copenhagen, Denmark ^[2] Univ Copenhagen, Fac Hlth & Med Sci, Med Chem Grp, Univ Pk 2, DK-2100 Copenhagen, Denmark ^[3] Univ Copenhagen, Fac Hlth & Med Sci, Mol & Cellular Pharmacol Grp, Univ Pk 2, DK-2100 Copenhagen, Denmark ^[4] McGill Univ, Fac Med, Dept Pharmacol & Therapeut, Bowie Lab, Montreal, PQ H3G 0B1, Canada ^[5]

发布时间 2017-07-08

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