In human retinoblastoma Y79 cells okadaic acid-parthenolide co-treatment induces synergistic apoptotic effects, with PTEN as a key player

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作者： DiFiore,R. ^[1] ; Drago-Ferrante,R. ^[2] ; D'Anneo,A. ^[3] ; Augello,G. ^[4] ; Carlisi,D. ; DeBlasio,A. ; Giuliano,M. ; Tesoriere,G. ; Vento,R.

作者单位： Institute of Biomedicine and Molecular Immunology Alberto Monroy, National Research Council (CNR), ^[1] Laboratory of Biochemistry, Department of Experimental Biomedicine and Clinical Neurosciences ^[2] Laboratory of Biochemistry, Department of Biological, Chemical and Pharmaceutical Sciences and ^[3] Institute for Cancer Research and Molecular Medicine, College of Science and Biotechnology, Temple ^[4]

关键词 Natural drugs Okadaic acid Oxidative stress Parthenolide PTEN/Akt/Mdm2/p53 pathway Retinoblastoma Synergistic apoptotic effects Y79 cells

发布时间 2014-04-03

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