Selinexor in combination with topotecan in patients with advanced or metastatic solid tumors: Results of an open-label, single-center, multi-arm phase Ib study

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作者： Thein, Kyaw Zin ^[1] ; Piha-Paul, Sarina A. ^[2] ; Tsimberidou, Apostolia ^[3] ; Karp, Daniel D. ^[4] ; Janku, Filip ^[5] ; Zarifa, Abdulrazzak ; Shah, Jatin ; Milton, Denai R. ; Bean, Stacie ; McQuinn, Lacey ; Gong, Jing ; Colen, Rivka ; Carter, Brett W. ; Subbiah, Vivek ; Ogbonna, Deby C. ; Pant, Shubham ; Meric-Bernstam, Funda ; Naing, Aung

作者单位： Univ Texas MD Anderson Canc Ctr, Div Canc Med, Phase Clin Trials Program 1, Dept Invest Canc ^[1] Karyopharm Therapeut, Newton, MA USA ^[2] Univ Texas MD Anderson Canc Ctr, Dept Biostat, Houston, TX 77030 USA ^[3] Univ Texas MD Anderson Canc Ctr, Div Diagnost Imaging, Dept Thorac Imaging, Houston, TX 77030 USA ^[4] Univ Texas MD Anderson Canc Ctr, Dept Diagnost Radiol, Houston, TX 77030 USA ^[5]

关键词 Selinexor KPT 330 Topotecan Metastatic solid tumors Selective inhibitor of nuclear export (SINE)

发布时间 2021-11-26

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