Clarifying the molecular mechanism of tomentosin-induced antiproliferative and proapoptotic effects in human multiple myeloma via gene expression profile and genetic interaction network analysis

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作者： Virdis, Patrizia ^[1] ; Migheli, Rossana ^[2] ; Bordoni, Valentina ^[3] ; Fiorentino, Francesco Paolo ^[4] ; Sanna, Luca ; Marchesi, Irene ; Pintore, Giorgio ; Galleri, Grazia ; Muroni, Maria Rosaria ; Bagella, Luigi ; Fozza, Claudio ; De Miglio, Maria Rosaria ; Podda, Luigi

作者单位： Kitos Biotech Srls, Porto Conte Ric, I-07100 Sassari, Sardinia, Italy ^[1] Univ Sassari, Dept Biomed Sci, I-07100 Sassari, Sardinia, Italy ^[2] Univ Sassari, Dept Med Surg & Expt Sci, 43B Viale San Pietro, I-07100 Sassari, Sardinia, Italy ^[3] Univ Sassari, Dept Chem & Pharm, I-07100 Sassari, Sardinia, Italy ^[4]

关键词 multiple myeloma tomentosin cytotoxicity apoptosis gene expression profiling cyclic AMP-dependent transcription factor ATF-4 DNA damage-inducible transcript 3 protein Protein-Protein Interaction network

发布时间 2021-12-08

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