A multi-kinase inhibitor APG-2449 enhances the antitumor effect of ibrutinib in esophageal squamous cell carcinoma via EGFR/FAK pathway inhibition

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作者： Luo, Qiu-Yun ^[1] ; Zhou, Su-Na ^[2] ; Pan, Wen-Tao ^[3] ; Sun, Jian ^[4] ; Yang, Li-Qiong ; Zhang, Lin ; Qiu, Miao-Zhen ; Yang, Da-Jun

作者单位： Sun Yat Sen Univ, Dept Clin Lab, Collaborat Innovat Ctr Canc Med, State Key Lab Oncol South China ^[1] Sun Yat Sen Univ, Dept Expt Res, Collaborat Innovat Ctr Canc Med, State Key Lab Oncol South China ^[2] Sun Yat Sen Univ, Dept Med Oncol, Collaborat Innovat Ctr Canc Med, State Key Lab Oncol South China ^[3] Sun Yat Sen Univ, Dept Clin Res, Collaborat Innovat Ctr Canc Med, State Key Lab Oncol South China ^[4]

关键词 FAK Ibrutinib EGFR ESCC Combination therapy

发布时间 2021-05-08

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Biochemical Pharmacology

2021年183卷

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A multi-kinase inhibitor APG-2449 enhances the antitumor effect of ibrutinib in esophageal squamous cell carcinoma via EGFR/FAK pathway inhibition

Biochemical Pharmacology

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Biochemical Pharmacology

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A multi-kinase inhibitor APG-2449 enhances the antitumor effect of ibrutinib in esophageal squamous cell carcinoma via EGFR/FAK pathway inhibition

Biochemical Pharmacology

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Biochemical Pharmacology

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