Design and synthesis of new potent N,N-bis(arylalkyl)piperazine derivatives as multidrug resistance (MDR) reversing agents

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作者： Dei, Silvia ^[1] ; Coronnello, Marcella ^[2] ; Bartolucci, Gianluca ^[3] ; Manetti, Dina ^[4] ; Romanelli, Maria Novella ; Udomtanakunchai, Chatchanok ; Salerno, Milena ; Teodori, Elisabetta

作者单位： Chiang Mai Univ, Fac Associated Med Sci, Dept Radiol Technol, Chiang Mai 50200, Thailand ^[1] Univ Paris 13, Sorbonne Paris Cite, Lab CSPBAT, CNRS,UMR 7244,UFR SMBH, 74 Rue Marcel Cochin, F ^[2] Univ Florence, Sect Pharmaceut & Nutraceut Sci, Dept Neurosci Psychol Drug Res & Childs Hlth, Via ^[3] Univ Florence, Sect Clin Pharmacol & Oncol, Dept Hlth Sci, Viale Pieraccini 6, I-50139 Florence ^[4]

关键词 MDR reversers P-gp modulators Piperazine derivatives Chemosensitizers Doxorubicin-resistant human erythroleukemia K562 cells (K562/DOX)Pirarubicin uptake

发布时间 2019-01-12

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European Journal of Medicinal Chemistry

2018年147卷

7-20页

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Design and synthesis of new potent N,N-bis(arylalkyl)piperazine derivatives as multidrug resistance (MDR) reversing agents

European Journal of Medicinal Chemistry

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European Journal of Medicinal Chemistry

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Design and synthesis of new potent N,N-bis(arylalkyl)piperazine derivatives as multidrug resistance (MDR) reversing agents

European Journal of Medicinal Chemistry

相似文献

European Journal of Medicinal Chemistry

相关期刊

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