Novel protease inhibitor-loaded Nanoparticle-in-Microparticle Delivery System leads to a dramatic improvement of the oral pharmacokinetics in dogs

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作者： Imperiale, Julieta C. ^[1] ; Nejamkin, Pablo ^[2] ; del Sole, Maria J. ^[3] ; Lanusse, Carlos E. ; Sosnik, Alejandro

作者单位： Univ Buenos Aires, Fac Pharm & Biochem, Dept Pharmaceut Technol, Buenos Aires, DF, Argentina ^[1] Technion Israel Inst Technol, Dept Mat Sci & Engn, Grp Pharmaceut Nanomat Sci, Haifa, Israel ^[2] Natl Univ Cent Buenos Aires, Fac Vet Sci, Small Anim Teaching Hosp, Tandil, Argentina ^[3]

关键词 HIV infection Protease inhibitors Indinavir free base Pure drug Nanoparticle-in-Microparticle Delivery System (NiMDS)Mucoadhesion Oral bioavailability

发布时间 2020-04-02

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Biomaterials

2015年37卷

383-394页

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Novel protease inhibitor-loaded Nanoparticle-in-Microparticle Delivery System leads to a dramatic improvement of the oral pharmacokinetics in dogs

Biomaterials

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Biomaterials

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Novel protease inhibitor-loaded Nanoparticle-in-Microparticle Delivery System leads to a dramatic improvement of the oral pharmacokinetics in dogs

Biomaterials

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Biomaterials

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