换一批γ-Galactosylceramide treatment before allergen sensitization promotes iNKT cell mediated induction of Treg cells, preventing Th2 cell responses in murine asthma
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关键词
AllergensBiological organsDiseasesMammalsT-cellsAirway inflammationAllergic asthmaDendritic cellsIntraperitoneal administrationIntraperitoneal injectionsProinflammatoryRegulatory t cellsTherapeutic strategyCytologyalpha galactosylceramideCD4 antigenhouse dust allergeninterleukin 2ovalbumintranscription factor FOXP3allergenalpha-galactosylceramidegalactosylceramideanimal cellanimal experimentanimal modelArticleasthmacell expansioncell maturationcellular immunitycontrolled studycytokine productiondendritic celldown regulationdrug mechanismfemaleimmunogenicityimmunostimulationin vivo studymousenatural killer T cellnonhumanpriority journalprovocation testregulatory T lymphocytesymptomT lymphocyte activationTh2 cellanimalBagg albino mousediseas
发布时间
2020-03-21
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The Journal of biological chemistry
5438-5455页
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