Validated UPLC-MS/MS method for simultaneous determination of simvastatin, simvastatin hydroxy acid and berberine in rat plasma: Application to the drug-drug pharmacokinetic interaction study of simvastatin combined with berberine after oral administration in rats

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作者： Liu, Mei ^[1] ; Su, Xianying ^[2] ; Li, Guofei ^[2] ; Zhao, Guilian ^[2] ; Zhao, Limei ^[2]

作者单位： Northeast Pharmaceut Shenyang Sci & Technol Dev C, Shenyang, Peoples R China ^[1] China Med Univ, Shengjing Hosp, Dept Pharm, Shenyang 110004, Peoples R China ^[2]

关键词 Simvastatin Berberine LC-MS-MS Determination Pharmacokinetics Drug-drug interaction

发布时间 2016-01-20

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Journal of chromatography, B. Analytical technologies in the biomedical and life sciences

2015年1006卷

8-15页

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Validated UPLC-MS/MS method for simultaneous determination of simvastatin, simvastatin hydroxy acid and berberine in rat plasma: Application to the drug-drug pharmacokinetic interaction study of simvastatin combined with berberine after oral administration in rats

Journal of chromatography, B. Analytical technologies in the biomedical and life sciences

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Journal of chromatography, B. Analytical technologies in the biomedical and life sciences

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Validated UPLC-MS/MS method for simultaneous determination of simvastatin, simvastatin hydroxy acid and berberine in rat plasma: Application to the drug-drug pharmacokinetic interaction study of simvastatin combined with berberine after oral administration in rats

Journal of chromatography, B. Analytical technologies in the biomedical and life sciences

相似文献

Journal of chromatography, B. Analytical technologies in the biomedical and life sciences

相关期刊

检索历史清除