Quantitative analysis of the effect of controlled -release formulation on nonlinear gastrointestinal absorption of P-glycoprotein substrate talinolol using physiologically based pharmacokinetic absorption model-论文-万方医学网

Quantitative analysis of the effect of controlled -release formulation on nonlinear gastrointestinal absorption of P-glycoprotein substrate talinolol using physiologically based pharmacokinetic absorption model

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作者： Suzuki, Satoru ^[1] ; Shirasaka, Yoshiyuki ^[2] ; Okada, Ren ; Eguchi, Akari ; Kishimoto, Hisanao ; Langguth, Peter ; Inoue, Katsuhisa

作者单位： Tokyo Univ Pharm & Life Sci, Sch Pharm, 1432-1 Horinouchi, Tokyo 1920392, Japan ^[1] Johannes Gutenberg Univ Mainz, Inst Pharm & Biochem, Staudingerweg 5, D-55099 Mainz, Germany ^[2]

关键词 Controlled release Sustained release Oral absorption P-glycoprotein Talinolol Physiologically based pharmacokinetic model

发布时间 2020-10-15

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Quantitative analysis of the effect of controlled -release formulation on nonlinear gastrointestinal absorption of P-glycoprotein substrate talinolol using physiologically based pharmacokinetic absorption model

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Quantitative analysis of the effect of controlled -release formulation on nonlinear gastrointestinal absorption of P-glycoprotein substrate talinolol using physiologically based pharmacokinetic absorption model

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