Fitness costs of rifampicin resistance in Mycobacterium tuberculosis are amplified under conditions of nutrient starvation and compensated by mutation in the β′ subunit of RNA polymerase

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作者： Song,T. ^[1] ; Park,Y. ^[2] ; Shamputa,I.C. ^[3] ; Seo,S. ^[4] ; Lee,S.Y. ^[5] ; Jeon,H.-S. ^[6] ; Choi,H. ^[7] ; Lee,M. ; Glynne,R.J. ; Barnes,S.W. ; Walker,J.R. ; Batalov,S. ; Yusim,K. ; Feng,S. ; Tung,C.-S. ; Theiler,J. ; Via,L.E. ; Boshoff,H.I.M. ; Murakami,K.S. ; Korber,B. ; Barry,C.E. ; Cho,S.-N.

作者单位： International Tuberculosis Research Center, Changwon, South Korea, Tuberculosis Research Section ^[1] Genomics Institute of the Novartis Research Foundation, San Diego, CA, United States ^[2] Los Alamos National Laboratory, Los Alamos, NM, United States ^[3] Tuberculosis Research Section, National Institute of Allergy and Infectious Disease, NIH, Bethesda ^[4] International Tuberculosis Research Center, Changwon, South Korea ^[5] Department of Biochemistry and Molecular Biology, Center for RNA Molecular Biology, Pennsylvania ^[6] International Tuberculosis Research Center, Changwon, South Korea, Department of Microbiology and ^[7]

发布时间 2014-05-30

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Molecular Microbiology

2014年91卷6期

1106-1119页

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Fitness costs of rifampicin resistance in Mycobacterium tuberculosis are amplified under conditions of nutrient starvation and compensated by mutation in the β′ subunit of RNA polymerase

Molecular Microbiology

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Molecular Microbiology

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Fitness costs of rifampicin resistance in Mycobacterium tuberculosis are amplified under conditions of nutrient starvation and compensated by mutation in the β′ subunit of RNA polymerase

Molecular Microbiology

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Molecular Microbiology

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