A randomized, double-blind, placebo-controlled, phase 2b Study to evaluate the safety and efficacy of recombinant human soluble thrombomodulin, ART-123, in patients with sepsis and suspected disseminated intravascular coagulation
作者:
Vincent,J.-L. [1]
;
Ramesh,M.K. [2]
;
Ernest,D. [3]
;
Larosa,S.P. [4]
;
Pachl,J. [5]
;
Aikawa,N. [6]
;
Hoste,E. [7]
;
Levy,H. [8]
;
Hirman,J. [9]
;
Levi,M. [10]
;
Daga,M. [11]
;
Kutsogiannis,D.J. [12]
;
Crowther,M. [13]
;
Bernard,G.R. [14]
;
Devriendt,J. [15]
;
Puigserver,J.V. [16]
;
Blanzaco,D.U. [17]
;
Esmon,C.T. [18]
;
Parrillo,J.E. [19]
;
Guzzi,L. [20]
;
Henderson,S.J. [21]
;
Pothirat,C. [22]
;
Mehta,P. [23]
;
Fareed,J. [24]
;
Talwar,D. [25]
;
Tsuruta,K. [26]
;
Gorelick,K.J. [27]
;
Osawa,Y. ;
Kaul,I.
作者单位:
Howard Levy Consulting LLC, Hopewell, NJ, United States
[1]
Metro Hospitals, Noida, India
[2]
Servei d'Urgències, Hospital Universitari Son Espases, Palma de Mallorca, Spain
[3]
Department of Intensive Care, CHU Brugmann, Brussels, Belgium
[4]
Oklahoma Medical Research Foundation, Howard Hughes Medical Institute, Oklahoma City, OK, United
[5]
Zymo Consulting Group LLC, Newtown Square, PA, United States
[6]
Mehta Hospital and Cardiopulmonary Care Centre, Ahmedabad, India
[7]
Department of Medicine, Vanderbilt University, Nashville, TN, United States
[8]
Department of Medicine, Monash University, Monash Medical Center, Clayton, VIC, Australia
[9]
Pacific Northwest Statistical Consulting, Woodinville, WA, United States
[10]
Division of Infectious Disease, Beverly Hospital/Lahey Health, Beverly, MA, United States
[11]
Asahi Kasei Pharma America Corporation, Waltham, MA, United States
[12]
Division of Pulmonary and Critical Care, Faculty of Medicine, Chiang Mai University, Chiang Mai
[13]
Department of Anesthesiology and Critical Care Medicine, Charles University Prague, Faculty
[14]
Heart and Vascular Hospital, Hackensack University Medical Center, New Jersey Medical School of
[15]
Department of Intensive Care, Hospital San Martín, Paraná, Argentina
[16]
Department of Medicine, McMaster University and St Joseph's Hospital, Hamilton, Canada
[17]
Department of Emergency and Critical Care Medicine, School of Medicine, Keio University, Shinjukuku
[18]
Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium
[19]
Florida Hospital, Orlando, FL, United States
[20]
Pathology and Pharmacology, Loyola University Medical Center, Maywood, IL, United States
[21]
Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta
[22]
Department of Vascular Medicine and Internal Medicine, Academic Medical Center, Amsterdam
[23]
Department of Intensive Care, Christchurch Hospital, Christchurch, New Zealand
[24]
Department of Intensive Care Medicine, Ghent University Hospital, Ghent University, Ghent, Belgium
[25]
Department of Medicine, Maulana Azad Medical College, New Delhi, India
[26]
Department of Surgery, Victoria Hospital, Bangalore Medical College and Research Institute
[27]
发布时间
2013-11-20
- 浏览2
Critical care medicine
Critical care medicine
2069-2079页
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