Blockade of C5 in Severe Acute Postinfectious Glomerulonephritis Associated With Anti-Factor H Autoantibody

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作者： Chehade, Hassib ^[1] ; Rotman, Samuel ^[2] ; Fremeaux-Bacchi, Veronique ^[3] ; Aubert, Vincent ^[4] ; Sadallah, Salima ^[5] ; Sifaki, Loukia ^[6] ; Salomon, Remi ; Pascual, Manuel

作者单位： Univ Hosp Lausanne CHUV, Serv Immunol, Lausanne, Switzerland ^[1] Hop Europeen Georges Pompidou, AP HP, Lab Immunol & Biol, Paris, France ^[2] Necker Childrens Hosp, Serv Pediat Nephrol, Paris, France ^[3] Univ Hosp Lausanne CHUV, Inst Pathol, Lausanne, Switzerland ^[4] Univ Hosp Lausanne CHUV, Pediat Nephrol Unit, Serv Pediat, Rue Bugnon 46, CH-1011 Lausanne ^[5] Univ Hosp Lausanne CHUV, Transplantat Ctr, Rue Bugnon 46, CH-1011 Lausanne, Switzerland ^[6]

关键词 Postinfectious glomerulonephritis (PIGN)crescentic PIGN terminal complement pathway blockade anti-C5 monoclonal antibody eculizumab acute kidney injury anti-factor H autoantibody complement CFH kidney function renal biopsy pediatric case report

发布时间 2017-04-15

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