Co-precipitation molecules hemopexin and transferrin may be key molecules for fibrillogenesis in TTR V30M amyloidogenesis

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作者： Ohta, Mika ^[1] ; Sugano, Aki ^[2] ; Hatano, Naoya ^[3] ; Sato, Hirotaka ^[1] ; Shimada, Hirofumi ^[4] ; Niwa, Hitoshi ^[5] ; Sakaeda, Toshiyuki ^[1] ; Tei, Hajime ^[5] ; Sakaki, Yoshiyuki ^[6] ; Yamamura, Ken-ichi ^[3] ; Takaoka, Yutaka ^[5]

作者单位： Kobe Univ Hosp, Div Med Informat & Bioinformat, Kobe, Hyogo 6500017, Japan ^[1] Iwate Med Univ, Div Anat & Cellular Pathol, Dept Pathol, Morioka, Iwate 0283694, Japan ^[2] Univ Tokyo, Inst Med Sci, Ctr Human Genome, Tokyo 1088639, Japan ^[3] Kobe Univ, Integrated Ctr Mass Spectrometry, Grad Sch Med, Kobe, Hyogo 6500017, Japan ^[4] Kumamoto Univ, Inst Mol Embryol & Genet, Kumamoto 8600811, Japan ^[5] Kyoto Pharmaceut Univ, Dept Phamacokinet, Kyoto 6078414, Japan ^[6]

关键词 Proteomic analysis TTR amyloidogenesis Hemopexin Transferrin Molecular dynamics simulation

发布时间 2018-05-31

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