Design, synthesis and evaluation of new quinazolin-4-one derivatives as apoptotic enhancers and autophagy inhibitors with potent antitumor activity

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作者： ElZahabi, Heba S. A. ^[1] ; Nafie, Mohamed S. ^[2] ; Osman, Dina ^[3] ; Elghazawy, Nehal H. ^[4] ; Soliman, Dalia H. ^[5] ; EL-Helby, Abdelghany Ali H. ; Arafa, Reem K.

作者单位： Zewail City Sci & Technol, Drug Design & Discovery Lab, Giza 12578, Egypt ^[1] Al Azhar Univ, Fac Pharm, Dept Pharmaceut Chem, Boys Branch, Cairo, Egypt ^[2] Suez Canal Univ, Fac Sci, Chem Dept, Ismailia 41522, Egypt ^[3] Al Azhar Univ, Fac Pharm, Dept Med & Pharmaceut Chem, Girls Branch, Cairo, Egypt ^[4] MSA Univ, Fac Pharm, Pharmaceut Chem Dept, 6th Of October City, Egypt ^[5]

关键词 Quinazolin-4-ones Breast cancer EGFR Cell cycle analysis Apoptosis Autophagy

发布时间 2021-11-26

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European Journal of Medicinal Chemistry

2021年222卷

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Design, synthesis and evaluation of new quinazolin-4-one derivatives as apoptotic enhancers and autophagy inhibitors with potent antitumor activity

European Journal of Medicinal Chemistry

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European Journal of Medicinal Chemistry

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Design, synthesis and evaluation of new quinazolin-4-one derivatives as apoptotic enhancers and autophagy inhibitors with potent antitumor activity

European Journal of Medicinal Chemistry

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European Journal of Medicinal Chemistry

相关期刊

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