SGLT2 Inhibition Mediates Protection from Diabetic Kidney Disease by Promoting Ketone Body-Induced mTORC1 Inhibition

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作者： Tomita, Issei ^[1] ; Kume, Shinji ^[2] ; Sugahara, Sho ^[3] ; Osawa, Norihisa ^[4] ; Yamahara, Kosuke ^[5] ; Yasuda-Yamahara, Mako ; Takeda, Naoko ; Chin-Kanasaki, Masami ; Kaneko, Tatsuroh ; Mayoux, Eric ; Mark, Michael ; Yanagita, Motoko ; Ogita, Hisakazu ; Araki, Shin-ichi ; Maegawa, Hiroshi

作者单位： Boehringer Ingelheim Pharma GmbH & Co KG, CardioMetab Dis Res, Birkendorfer Str 65, D-88397 ^[1] Nippon Boehringer Ingelheim Co Ltd, Med Div, Shinagawa Ku, 2-1-1 Osaki, Tokyo 1416017, Japan ^[2] Shiga Univ Med Sci, Dept Biochem & Mol Biol, Div Mol Med Biochem, Tsukinowa Cho, Otsu, Shiga ^[3] Shiga Univ Med Sci, Dept Med, Tsukinowa Cho, Otsu, Shiga 5202192, Japan ^[4] Kyoto Univ, Grad Sch Med, Dept Nephrol, Sakyo Ku, 54 Shogoin Kawahara Cho, Kyoto 6068507, Japan ^[5]

发布时间 2021-07-24

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Cell metabolism

2020年32卷3期

404-419页

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SGLT2 Inhibition Mediates Protection from Diabetic Kidney Disease by Promoting Ketone Body-Induced mTORC1 Inhibition

Cell metabolism

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Cell metabolism

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SGLT2 Inhibition Mediates Protection from Diabetic Kidney Disease by Promoting Ketone Body-Induced mTORC1 Inhibition

Cell metabolism

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Cell metabolism

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