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Week 96 efficacy and safety results of the phase 3, randomized EMERALD trial to evaluate switching from boosted-protease inhibitors plus emtricitabine/tenofovir disoproxil fumarate regimens to the once daily, single-tablet regimen of darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) in treatment-experienced, virologically-suppressed adults living with HIV-1

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第一作者: Eron, Joseph J.
作者: Eron, Joseph J. [1] ; Orkin, Chloe [2] ; Cunningham, Douglas [3] ; Pulido, Federico [4] ; Post, Frank A. [5] ; De Wit, Stephane [6] ; Lathouwers, Erkki [7] ; Hufkens, Veerle [8] ; Jezorwski, John [9] ; Petrovic, Romana [10] ; Brown, Kimberley [11] ; Van Landuyt, Erika [12] ; Opsomer, Magda [13] ; De Wit, S. [14] ; Florence, E. [15] ; Moutschen, M. [16] ; Van Wijngaerden, E. [17] ; Vandekerckhove, L. [18] ; Vandercam, B. [19] ; Brunetta, J. [20] ; Conway, B. [21] ; Klein, M. [22] ; Murphy, D. [23] ; Rachlis, A. [24] ; Shafran, S. [25] ; Walmsley, S. [26] ; Ajana, F. [27] ; Cotte, L. [28] ; Girardy, P. -M. [29] ; Katlama, C. [30] ; Molina, J. -M. [31] ; Poizot-Martin, I. [32] ; Raffi, F. [33] ; Rey, D. [34] ; Reynes, J. [35] ; Teicher, E. [36] ; Yazdanpanah, Y. [37] ; Gasiorowski, J. [38] ; Halota, W. [39] ; Horban, A. [40] ; Piekarska, A. [41] ; Witor, A. [42] ; Arribas, J. R. [43] ; Perez-Valero, I. [44] ; Berenguer, J. [45] ; Casado, J. [46] ; Gatell, J. M. [47] ; Gutierrez, F. [48] ; Galindo, M. J. [49] ; Gutierrez, M. D. M. [50] ; Iribarren, J. A. [51] ; Knobel, H. [52] ; Negredo, E. [53] ; Pineda, J. A. [54] ; Podzamczer, D. [55] ; Portilla Sogorb, J. [56] ; Pulido, F. [57] ; Ricart, C. [58] ; Rivero, A. [59] ; Santos Gil, I. [60] ; Blaxhult, A. [61] ; Flamholc, L. [62] ; Gisslen, M. [63] ; Thalme, A. [64] ; Fehr, J. [65] ; Rauch, A. [66] ; Stoeckle, M. [67] ; Clarke, A. [68] ; Gazzard, B. G. [69] ; Johnson, M. A. [70] ; Orkin, C. [71] ; Post, F. [72] ; Ustianowski, A. [73] ; Waters, L. [74] ; Bailey, J. [75] ; Benson, P. [76] ; Bhatti, L. [77] ; Brar, I. [78] ; Bredeek, U. F. [79] ; Brinson, C. [80] ; Crofoot, G. [81] ; Cunningham, D. [82] ; DeJesus, E. [83] ; Dietz, C. [84] ; Dretler, R. [85] ; Eron, J. [86] ; Felizarta, F. [87] ; Fichtenbaum, C. [88] ; Gallant, J. [89] ; Gathe, J. [90] ; Hagins, D. [91] ; Henn, S. [92] ; Henry, W. K. [93] ; Huhn, G. [94] ; Jain, M. [95] ; Lucasti, C. [96] ; Martorell, C. [97] ; McDonald, C. [98] ; Mills, A. [99] ; Morales-Ramirez, J. [100] ; Mounzer, K. [101] ; Nahass, R. [102] ; Olivet, H. [103] ; Osiyemi, O. [104] ; Prelutsky, D. [105] ; Ramgopal, M. [106] ; Rashbaum, B. [107] ; Richmond, G. [108] ; Ruane, P. [109] ; Scarsella, A. [110] ; Scribner, A. ; Shalit, P. ; Shamblaw, D. ; Slim, J. ; Tashima, K. ; Voskuhl, G. ; Ward, D. ; Wilkin, A. ; de Vente, J.
作者单位: DCOL Ctr Clin Res, Longview, TX USA [1] La Playa Med Grp, San Diego, CA USA [2] Pueblo Family Phys, Pueblo, AZ USA [3] Queen Mary Univ, London, England [4] Kings Coll Hosp NHS Fdn Trust, London, England [5] Univ Autonoma Barcelona, Hosp del Mar, Barcelona, Spain [6] CHU Hotel Dieu, Nantes, France [7] Washington Univ, Sch Med, Univ Minnesota, Dept Med, St Louis, MO USA [8] Washington Univ, Sch Med, Dept Internal Med, St Louis, MO 63110 USA [9] Tourcoing Hosp, Dept Infect Dis, Tourcoing, France [10] Malmo Univ Hosp, Dept Infect Dis, S-20502 Malmo, Sweden [11] McGill Univ, Div Infect Dis, Fac Med, Hlth Ctr, Montreal, PQ, Canada [12] Univ Toronto, Dept Med, Toronto, ON, Canada [13] 14AP HP Bichat, Paris, France [14] ID Care, Hillsborough, NJ USA [15] Johns Hopkins Univ, Sch Med, Dept Med, Baltimore, MD 21205 USA [16] Chelsea & Westminster Hosp, Dept HIV Genitourinary Med, St Stephens Ctr, London, England [17] Metropolis Med PC, San Francisco, CA USA [18] Univ Paris Diderot, St Louis Hosp, AP HP, Dept Infect Dis, Paris, France [19] Brown Univ, Miriam Hosp, Warren Alpert Med Sch, Providence, RI USA [20] Univ N Carolina, Sch Med, Chapel Hill, NC 27515 USA [21] Karolinska Univ Hosp, Dept Infect Dis, Stockholm, Sweden [22] Univ Hosp Basel, Div Infect Dis & Hosp Epidemiol, Dept Med, Basel, Switzerland [23] Dupont Circle Phys Grp, Washington, DC USA [24] Philadelphia FIGHT, 1233 Locust St,3rd Floor, Philadelphia, PA USA [25] Univ Gothenburg, Dept Infect Dis, Gothenburg, Sweden [26] Cent Texas Clin Res, Austin, TX USA [27] Wake Forest Sch Med, Winston Salem, NC 27101 USA [28] Pacific Oaks Med Grp, Beverly Hills, CA USA [29] Hop Univ Strasbourg, HIV Infect Care Ctr, Le Trait Union, Strasbourg, France [30] Hosp Santa Creu & Sant Pau, Inst Recerca, Dept Infect Dis, HIV Infect Unit, Barcelona, Spain [31] Univ Coll London Hosp, London, England [32] Whitman Walker Hlth, Washington, DC USA [33] Hop Bicetre, AP HP, Dept Infect Dis, Le Kremlin Bicetre, France [34] Peter Shalit MD & Associates, 901 Boren Ave,Suite 850, Seattle, WA 98104 USA [35] Seton Hall Univ, Dept Infect Dis, S Orange, NJ 07079 USA [36] Univ Texas Southwestern Med Ctr Dallas, Dept Internal Med, Dallas, TX 75390 USA [37] Univ Paris 06, Paris, France [38] Royal Free London NHS Fdn Trust, Dept HIV Med, London, England [39] Crofoot Res Ctr, Houston, TX USA [40] Hosp Univ Donostia, San Sebastian, Spain [41] Hosp Univ Bellvitge, IDIBELL, Barcelona, Spain [42] Living Hope Fdn, Long Beach, CA USA [43] HCB, Dept Infect Dis, Barcelona, Spain [44] Southern Calif Mens Med Grp, Los Angeles, CA USA [45] Infect Dis Specialists Atlanta, Atlanta, GA USA [46] Janssen Res & Dev, Pennington, NJ USA [47] North Manchester Gen Hosp, Reg Infect Dis Unit, Manchester, Lancs, England [48] Wroclaw Med Univ, Dept Infect Dis Liver Dis & Acquired Immune Defic, Independent Lab Monitoring [49] Hosp Civils Lyon, Hop Croix Rousse, Lyon, France [50] Be Well Med, Berkley, MI USA [51] Nicolaus Copernicus Univ, Dept Infect Dis & Hepatol, Bydgoszcz, Poland [52] Univ Ghent, Ghent, Belgium [53] Midway Immunol Ctr, Ft Pierce, FL USA [54] Univ N Carolina, Sch Med, Chapel Hill, NC 27599 USA [55] Inst Trop Med, Antwerp, Belgium [56] 3535 San Dimas St,Suite 24, Bakersfield, CA 93301 USA [57] Maple Leaf Med Clin, Toronto, ON, Canada [58] Reg Hosp, Out Patients Clin Immune Deficiency, Chorzow, Poland [59] Hosp Gen Univ Alicante, Med Interna, Alicante, Spain [60] Brighton & Sussex Univ Hosp NHS Trust, Royal Sussex Cty Hosp, Claude Nicol Ctr, Brighton, E Sussex [61] Ruth M Rothstein CORE Ctr, Chicago, IL USA [62] Clin Univ St Luc, AIDS Reference Ctr, B-1200 Brussels, Belgium [63] UCM, Hosp 12 Octubre, Imas12, HIV Unit, Madrid, Spain [64] AIDS Healthcare Fdn, Beverly Hills, CA USA [65] Montpellier Univ Hosp, Montpellier, France [66] Henry Ford Hosp, Detroit, MI 48202 USA [67] Community Res Initiat New England, Boston, MA USA [68] Univ Leuven, KU Leuven, Univ Hosp, Dept Gen Internal Med, Leuven, Belgium [69] Sunnybrook Hlth Sci Ctr, Toronto, ON, Canada [70] Janssen Pharmaceut NV, Beerse, Belgium [71] Orlando Immunol Ctr, Orlando, FL USA [72] Ruane Clin Res Grp, Los Angeles, CA USA [73] Chatham Care Ctr, Georgia Dept Publ Hlth, Coastal Hlth Dist, Savannah, GA USA [74] Tarrant Cty Infect Dis Associates, Ft Worth, TX USA [75] Univ Libre Bruxelles, St Pierre Univ Hosp, Brussels, Belgium [76] Triple O Res Inst PA, W Palm Beach, FL USA [77] Broward Gen Med Ctr, Ft Lauderdale, FL USA [78] South Jersey Infect Dis, Somers Point, NJ USA [79] Univ Cincinnati, Coll Med, Cincinnati, OH USA [80] Med Univ Warsaw, Dept Adults Infect Dis, Warsaw, Poland [81] Hosp Clin Univ Valencia, Valencia, Spain [82] Kansas City Free Hlth Clin, HIV Med, Kansas City, MO USA [83] Hop La Pitie Salpetriere, HIV Clin Res Unit, Paris, France [84] Soder Sjukhuset, Dept Infect Dis, Venhalsan, Stockholm, Sweden [85] Hosp Gen Univ Gregorio Maranon, Madrid 28007, Spain [86] Med Univ Lodz, Dept Infect Dis & Hepatol, Lodz, Poland [87] Hosp Univ Elche, Infect Dis Unit, Alicante, Spain [88] Inst Natl Sante Publ Quebec, Montreal, PQ, Canada [89] Germans Trias & Pujol Univ Hosp, Lluita Sida Fdn, Barcelona, Spain [90] Univ Valencia, Dept Microbiol, Sch Med, Valencia, Spain [91] Hosp Univ Princesa, Unidad Enfermedades Infecciosas, Madrid, Spain [92] Clin Res Puerto Rico Inc, San Juan, PR USA [93] Univ Bern, Inselspital, Dept Infect Dis, Bern Univ Hosp, Bern, Switzerland [94] Vancouver Infect Dis Ctr, Vancouver, BC, Canada [95] Dept La Paz Hosp, Madrid, Spain [96] Cordoba Univ, Inst Maimonides Invest Biomed Cordoba IMIBIC, Hosp Univ Reina Sofia, Infect Dis Unit [97] Hosp Univ Valme, Unit Infect Dis & Microbiol, Seville, Spain [98] Southwest CARE Ctr, Santa Fe, NM USA [99] Univ Hlth Network, Toronto, ON, Canada [100] AIDS Arms Inc, Dallas, TX USA [101] UCM, Hosp 12 Octubre, HIV Unit, Imas12, Madrid, Spain [102] Capital Med Associates, Washington, DC USA [103] Hosp Univ La Paz, IdiPAZ, Madrid, Spain [104] Liege Univ Hosp, Dept Infect Dis, Liege, Belgium [105] Infect Dis & Res Inst, Springfield, MA USA [106] Therapeut Concepts, Houston, TX USA [107] Ramon & Cajal Hosp, Dept Infect Dis, Madrid, Spain [108] Aix Marseille Univ, St Marguerite Univ Hosp, Clin Immunohematol Dept, Marseille, France [109] Univ Hosp Zurich, Div Infect Dis & Hosp Epidemiol, Zurich, Switzerland [110]
发布时间 2020-04-15
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Antiviral Research

Antiviral Research

2019年170卷

Article 104543-Article 104543页

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