Week 96 efficacy and safety results of the phase 3, randomized EMERALD trial to evaluate switching from boosted-protease inhibitors plus emtricitabine/tenofovir disoproxil fumarate regimens to the once daily, single-tablet regimen of darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) in treatment-experienced, virologically-suppressed adults living with HIV-1
第一作者:
Eron, Joseph J.
作者:
Eron, Joseph J. [1]
;
Orkin, Chloe [2]
;
Cunningham, Douglas [3]
;
Pulido, Federico [4]
;
Post, Frank A. [5]
;
De Wit, Stephane [6]
;
Lathouwers, Erkki [7]
;
Hufkens, Veerle [8]
;
Jezorwski, John [9]
;
Petrovic, Romana [10]
;
Brown, Kimberley [11]
;
Van Landuyt, Erika [12]
;
Opsomer, Magda [13]
;
De Wit, S. [14]
;
Florence, E. [15]
;
Moutschen, M. [16]
;
Van Wijngaerden, E. [17]
;
Vandekerckhove, L. [18]
;
Vandercam, B. [19]
;
Brunetta, J. [20]
;
Conway, B. [21]
;
Klein, M. [22]
;
Murphy, D. [23]
;
Rachlis, A. [24]
;
Shafran, S. [25]
;
Walmsley, S. [26]
;
Ajana, F. [27]
;
Cotte, L. [28]
;
Girardy, P. -M. [29]
;
Katlama, C. [30]
;
Molina, J. -M. [31]
;
Poizot-Martin, I. [32]
;
Raffi, F. [33]
;
Rey, D. [34]
;
Reynes, J. [35]
;
Teicher, E. [36]
;
Yazdanpanah, Y. [37]
;
Gasiorowski, J. [38]
;
Halota, W. [39]
;
Horban, A. [40]
;
Piekarska, A. [41]
;
Witor, A. [42]
;
Arribas, J. R. [43]
;
Perez-Valero, I. [44]
;
Berenguer, J. [45]
;
Casado, J. [46]
;
Gatell, J. M. [47]
;
Gutierrez, F. [48]
;
Galindo, M. J. [49]
;
Gutierrez, M. D. M. [50]
;
Iribarren, J. A. [51]
;
Knobel, H. [52]
;
Negredo, E. [53]
;
Pineda, J. A. [54]
;
Podzamczer, D. [55]
;
Portilla Sogorb, J. [56]
;
Pulido, F. [57]
;
Ricart, C. [58]
;
Rivero, A. [59]
;
Santos Gil, I. [60]
;
Blaxhult, A. [61]
;
Flamholc, L. [62]
;
Gisslen, M. [63]
;
Thalme, A. [64]
;
Fehr, J. [65]
;
Rauch, A. [66]
;
Stoeckle, M. [67]
;
Clarke, A. [68]
;
Gazzard, B. G. [69]
;
Johnson, M. A. [70]
;
Orkin, C. [71]
;
Post, F. [72]
;
Ustianowski, A. [73]
;
Waters, L. [74]
;
Bailey, J. [75]
;
Benson, P. [76]
;
Bhatti, L. [77]
;
Brar, I. [78]
;
Bredeek, U. F. [79]
;
Brinson, C. [80]
;
Crofoot, G. [81]
;
Cunningham, D. [82]
;
DeJesus, E. [83]
;
Dietz, C. [84]
;
Dretler, R. [85]
;
Eron, J. [86]
;
Felizarta, F. [87]
;
Fichtenbaum, C. [88]
;
Gallant, J. [89]
;
Gathe, J. [90]
;
Hagins, D. [91]
;
Henn, S. [92]
;
Henry, W. K. [93]
;
Huhn, G. [94]
;
Jain, M. [95]
;
Lucasti, C. [96]
;
Martorell, C. [97]
;
McDonald, C. [98]
;
Mills, A. [99]
;
Morales-Ramirez, J. [100]
;
Mounzer, K. [101]
;
Nahass, R. [102]
;
Olivet, H. [103]
;
Osiyemi, O. [104]
;
Prelutsky, D. [105]
;
Ramgopal, M. [106]
;
Rashbaum, B. [107]
;
Richmond, G. [108]
;
Ruane, P. [109]
;
Scarsella, A. [110]
;
Scribner, A. ;
Shalit, P. ;
Shamblaw, D. ;
Slim, J. ;
Tashima, K. ;
Voskuhl, G. ;
Ward, D. ;
Wilkin, A. ;
de Vente, J.
作者单位:
DCOL Ctr Clin Res, Longview, TX USA
[1]
La Playa Med Grp, San Diego, CA USA
[2]
Pueblo Family Phys, Pueblo, AZ USA
[3]
Queen Mary Univ, London, England
[4]
Kings Coll Hosp NHS Fdn Trust, London, England
[5]
Univ Autonoma Barcelona, Hosp del Mar, Barcelona, Spain
[6]
CHU Hotel Dieu, Nantes, France
[7]
Washington Univ, Sch Med, Univ Minnesota, Dept Med, St Louis, MO USA
[8]
Washington Univ, Sch Med, Dept Internal Med, St Louis, MO 63110 USA
[9]
Tourcoing Hosp, Dept Infect Dis, Tourcoing, France
[10]
Malmo Univ Hosp, Dept Infect Dis, S-20502 Malmo, Sweden
[11]
McGill Univ, Div Infect Dis, Fac Med, Hlth Ctr, Montreal, PQ, Canada
[12]
Univ Toronto, Dept Med, Toronto, ON, Canada
[13]
14AP HP Bichat, Paris, France
[14]
ID Care, Hillsborough, NJ USA
[15]
Johns Hopkins Univ, Sch Med, Dept Med, Baltimore, MD 21205 USA
[16]
Chelsea & Westminster Hosp, Dept HIV Genitourinary Med, St Stephens Ctr, London, England
[17]
Metropolis Med PC, San Francisco, CA USA
[18]
Univ Paris Diderot, St Louis Hosp, AP HP, Dept Infect Dis, Paris, France
[19]
Brown Univ, Miriam Hosp, Warren Alpert Med Sch, Providence, RI USA
[20]
Univ N Carolina, Sch Med, Chapel Hill, NC 27515 USA
[21]
Karolinska Univ Hosp, Dept Infect Dis, Stockholm, Sweden
[22]
Univ Hosp Basel, Div Infect Dis & Hosp Epidemiol, Dept Med, Basel, Switzerland
[23]
Dupont Circle Phys Grp, Washington, DC USA
[24]
Philadelphia FIGHT, 1233 Locust St,3rd Floor, Philadelphia, PA USA
[25]
Univ Gothenburg, Dept Infect Dis, Gothenburg, Sweden
[26]
Cent Texas Clin Res, Austin, TX USA
[27]
Wake Forest Sch Med, Winston Salem, NC 27101 USA
[28]
Pacific Oaks Med Grp, Beverly Hills, CA USA
[29]
Hop Univ Strasbourg, HIV Infect Care Ctr, Le Trait Union, Strasbourg, France
[30]
Hosp Santa Creu & Sant Pau, Inst Recerca, Dept Infect Dis, HIV Infect Unit, Barcelona, Spain
[31]
Univ Coll London Hosp, London, England
[32]
Whitman Walker Hlth, Washington, DC USA
[33]
Hop Bicetre, AP HP, Dept Infect Dis, Le Kremlin Bicetre, France
[34]
Peter Shalit MD & Associates, 901 Boren Ave,Suite 850, Seattle, WA 98104 USA
[35]
Seton Hall Univ, Dept Infect Dis, S Orange, NJ 07079 USA
[36]
Univ Texas Southwestern Med Ctr Dallas, Dept Internal Med, Dallas, TX 75390 USA
[37]
Univ Paris 06, Paris, France
[38]
Royal Free London NHS Fdn Trust, Dept HIV Med, London, England
[39]
Crofoot Res Ctr, Houston, TX USA
[40]
Hosp Univ Donostia, San Sebastian, Spain
[41]
Hosp Univ Bellvitge, IDIBELL, Barcelona, Spain
[42]
Living Hope Fdn, Long Beach, CA USA
[43]
HCB, Dept Infect Dis, Barcelona, Spain
[44]
Southern Calif Mens Med Grp, Los Angeles, CA USA
[45]
Infect Dis Specialists Atlanta, Atlanta, GA USA
[46]
Janssen Res & Dev, Pennington, NJ USA
[47]
North Manchester Gen Hosp, Reg Infect Dis Unit, Manchester, Lancs, England
[48]
Wroclaw Med Univ, Dept Infect Dis Liver Dis & Acquired Immune Defic, Independent Lab Monitoring
[49]
Hosp Civils Lyon, Hop Croix Rousse, Lyon, France
[50]
Be Well Med, Berkley, MI USA
[51]
Nicolaus Copernicus Univ, Dept Infect Dis & Hepatol, Bydgoszcz, Poland
[52]
Univ Ghent, Ghent, Belgium
[53]
Midway Immunol Ctr, Ft Pierce, FL USA
[54]
Univ N Carolina, Sch Med, Chapel Hill, NC 27599 USA
[55]
Inst Trop Med, Antwerp, Belgium
[56]
3535 San Dimas St,Suite 24, Bakersfield, CA 93301 USA
[57]
Maple Leaf Med Clin, Toronto, ON, Canada
[58]
Reg Hosp, Out Patients Clin Immune Deficiency, Chorzow, Poland
[59]
Hosp Gen Univ Alicante, Med Interna, Alicante, Spain
[60]
Brighton & Sussex Univ Hosp NHS Trust, Royal Sussex Cty Hosp, Claude Nicol Ctr, Brighton, E Sussex
[61]
Ruth M Rothstein CORE Ctr, Chicago, IL USA
[62]
Clin Univ St Luc, AIDS Reference Ctr, B-1200 Brussels, Belgium
[63]
UCM, Hosp 12 Octubre, Imas12, HIV Unit, Madrid, Spain
[64]
AIDS Healthcare Fdn, Beverly Hills, CA USA
[65]
Montpellier Univ Hosp, Montpellier, France
[66]
Henry Ford Hosp, Detroit, MI 48202 USA
[67]
Community Res Initiat New England, Boston, MA USA
[68]
Univ Leuven, KU Leuven, Univ Hosp, Dept Gen Internal Med, Leuven, Belgium
[69]
Sunnybrook Hlth Sci Ctr, Toronto, ON, Canada
[70]
Janssen Pharmaceut NV, Beerse, Belgium
[71]
Orlando Immunol Ctr, Orlando, FL USA
[72]
Ruane Clin Res Grp, Los Angeles, CA USA
[73]
Chatham Care Ctr, Georgia Dept Publ Hlth, Coastal Hlth Dist, Savannah, GA USA
[74]
Tarrant Cty Infect Dis Associates, Ft Worth, TX USA
[75]
Univ Libre Bruxelles, St Pierre Univ Hosp, Brussels, Belgium
[76]
Triple O Res Inst PA, W Palm Beach, FL USA
[77]
Broward Gen Med Ctr, Ft Lauderdale, FL USA
[78]
South Jersey Infect Dis, Somers Point, NJ USA
[79]
Univ Cincinnati, Coll Med, Cincinnati, OH USA
[80]
Med Univ Warsaw, Dept Adults Infect Dis, Warsaw, Poland
[81]
Hosp Clin Univ Valencia, Valencia, Spain
[82]
Kansas City Free Hlth Clin, HIV Med, Kansas City, MO USA
[83]
Hop La Pitie Salpetriere, HIV Clin Res Unit, Paris, France
[84]
Soder Sjukhuset, Dept Infect Dis, Venhalsan, Stockholm, Sweden
[85]
Hosp Gen Univ Gregorio Maranon, Madrid 28007, Spain
[86]
Med Univ Lodz, Dept Infect Dis & Hepatol, Lodz, Poland
[87]
Hosp Univ Elche, Infect Dis Unit, Alicante, Spain
[88]
Inst Natl Sante Publ Quebec, Montreal, PQ, Canada
[89]
Germans Trias & Pujol Univ Hosp, Lluita Sida Fdn, Barcelona, Spain
[90]
Univ Valencia, Dept Microbiol, Sch Med, Valencia, Spain
[91]
Hosp Univ Princesa, Unidad Enfermedades Infecciosas, Madrid, Spain
[92]
Clin Res Puerto Rico Inc, San Juan, PR USA
[93]
Univ Bern, Inselspital, Dept Infect Dis, Bern Univ Hosp, Bern, Switzerland
[94]
Vancouver Infect Dis Ctr, Vancouver, BC, Canada
[95]
Dept La Paz Hosp, Madrid, Spain
[96]
Cordoba Univ, Inst Maimonides Invest Biomed Cordoba IMIBIC, Hosp Univ Reina Sofia, Infect Dis Unit
[97]
Hosp Univ Valme, Unit Infect Dis & Microbiol, Seville, Spain
[98]
Southwest CARE Ctr, Santa Fe, NM USA
[99]
Univ Hlth Network, Toronto, ON, Canada
[100]
AIDS Arms Inc, Dallas, TX USA
[101]
UCM, Hosp 12 Octubre, HIV Unit, Imas12, Madrid, Spain
[102]
Capital Med Associates, Washington, DC USA
[103]
Hosp Univ La Paz, IdiPAZ, Madrid, Spain
[104]
Liege Univ Hosp, Dept Infect Dis, Liege, Belgium
[105]
Infect Dis & Res Inst, Springfield, MA USA
[106]
Therapeut Concepts, Houston, TX USA
[107]
Ramon & Cajal Hosp, Dept Infect Dis, Madrid, Spain
[108]
Aix Marseille Univ, St Marguerite Univ Hosp, Clin Immunohematol Dept, Marseille, France
[109]
Univ Hosp Zurich, Div Infect Dis & Hosp Epidemiol, Zurich, Switzerland
[110]
发布时间
2020-04-15
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Antiviral Research
Antiviral Research
Article 104543-Article 104543页
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