SP174 Antibody Lacks Specificity for NRAS Q61R and Cross-Reacts With HRAS and KRAS Q61R Mutant Proteins in Malignant Melanoma

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作者： Felisiak-Golabek, Anna ^[1] ; Inaguma, Shingo ^[2] ; Kowalik, Artur ^[3] ; Wasag, Bartosz ^[4] ; Wang, Zeng-Feng ^[5] ; Zieba, Sebastian ^[6] ; Pieciak, Liliana ^[7] ; Rys, Janusz ; Kopczynski, Janusz ; Sarlomo-Rikala, Maarit ; Gozdz, Stanislaw ; Lasota, Jerzy ; Miettinen, Markku

作者单位： HUSLab Pathol, Helsinki, Finland ^[1] NCI, Pathol Lab, 10 Ctr Dr,Bldg 10,Room B1B47, Bethesda, MD 20892 USA ^[2] Med Univ Gdansk, Dept Biol & Genet, Gdansk, Poland ^[3] Holycross Canc Ctr, Dept Clin Oncol, Kielce, Poland ^[4] Holycross Canc Ctr, Dept Mol Diagnost, Kielce, Poland ^[5] Maria Sklodowska Curie Mem Inst Oncol, Dept Tumor Pathol, Krakow, Poland ^[6] Holycross Canc Ctr, Dept Surg Pathol, Kielce, Poland ^[7]

关键词 RAS mutations immunohistochemistry HRAS KRAS and NRAS Q61R-mutant proteins SP174 antibody Sanger sequencing qPCR Ion Torrent next-generation sequencing

发布时间 2018-06-26

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