A phase I trial and pharmacokinetic study of a 24-hour infusion of trabectedin (Yondelis?, ET-743) in children and adolescents with relapsed or refractory solid tumors

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作者： Chuk,M.K. ^[1] ; Aikin,A. ^[2] ; Whitcomb,T. ^[3] ; Widemann,B.C. ^[4] ; Zannikos,P. ^[5] ; Bayever,E. ; Balis,F.M. ; Fox,E.

作者单位： Pediatric Oncology Branch, National Cancer Institute, Bethesda, MD, United States ^[1] Johnson and Johnson Pharmaceutical R and D, LLC, Titusville, NJ, United States ^[2] The Children's Hospital of Philadelphia, Philadelphia, PA, United States ^[3] Johnson and Johnson Pharmaceutical R and D, LLC, Raritan, NJ, United States ^[4] Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, United States ^[5]

关键词 Pediatrics Pharmacokinetics Phase I clinical trial Trabectedin

发布时间 2013-11-20

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